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Trefoil Factor 2 Recombinant Protein

ArtNr PRS-40-291-0.005mg
Hersteller ProSci
Menge 0.005 mg
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against other
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias SP, SML1, Trefoil factor 2, Spasmolysin, SP
Lieferbar
Storage Conditions
The lyophilized Trefoil Factor 2 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted Trefoil Factor 2 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing Trefoil Factor 2 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Disclaimer
This product is for research use only.
Purity
Greater than 98% by SDS-PAGE gel and HPLC analyses.

Endotoxin level is less than 0.1 ng per μ g (1EU/μ g).
Background
The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal defense and repair. TFF2 has been shown to inhibit gastrointestinal motility and gastric acid secretion. Recent data suggests a potential role for TFF2 in acute and chronic asthma (Nikolaidis, N.M. et al. Am. Journal Respir. Cell Mol. Biol. (2003) 4: 458-464). Recombinant human TFF2 is a 12.0 kDa polypeptide of 106 amino acid residues, which includes a 40-amino acid trefoil motif containing three conserved intramolecular disulfide bonds.
Accession #
NP_005414.1
Ncbi Gene Id #
7032
Ncbi Official Symbol
TFF2
Ncbi Official Full Name
trefoil factor 2
Ncbi Organism
Homo sapiens
Swissprot #
Q03403
Sequence
EKPSPCQCSR LSPHNRTNCG FPGITSDQCF DNGCCFDSSV TGVPWCFHPL PKQESDQCVM EVSDRRNCGY PGISPEECAS RKCCFSNFIF EVPWCFFPKS VEDCHY
Biological Activity
Assay 1: Biological activity was determined by its ability to chemoattract human monocytes using a concentration range of 1.0 - 10.0 μ g/mL.

Assay 2: Biological activity was determined by its ability to chemoattract human MCF - 7 cells using a concentration range of 1.0 - 10.0 ng/mL.
Protein Gi#
4885629
Peptide Sequence
EKPSPCQCSR LSPHNRTNCG FPGITSDQCF DNGCCFDSSV TGVPWCFHPL PKQESDQCVM EVSDRRNCGY PGISPEECAS RKCCFSNFIF EVPWCFFPKS VEDCHY

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.005 mg
Lieferbar: In stock
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