ArtNr |
PRS-11-274-0.1mg |
Hersteller |
ProSci
|
Menge |
0.1 mg |
Kategorie |
|
Typ |
Proteins Recombinant |
Format |
Lyophilized |
Applikationen |
WB, ELISA |
Specific against |
other |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
CD24,CD24A |
Lieferbar |
|
Applications |
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 5.0 kDa. The protein migrates as 19-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Applications |
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 5.0 kDa. The protein migrates as 19-33 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Buffer |
PBS, pH7.4 |
Storage Conditions |
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles. |
Disclaimer |
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures. |
Predicted Molecular Weight |
5.0 kDa |
Purity |
>90% as determined by SDS-PAGE. |
Background |
CD24 may have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity. |
1St Image Caption3 |
Human CD24, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 90%. |
Background References 1 |
Suzuki T1, et al. 2001. J Immunol. 166(9):5567-77. |
Background References 2 |
Chen Z, et al. 2017. Biomed Pharmacother. 90:427-436. |
Background References 3 |
Eyvazi S, et al. 2018. Curr Cancer Drug Targets. 18(4):328-336. |
Accession # |
NP_001278666.1 |
Ncbi Gene Id # |
100133941 |
Ncbi Official Symbol |
CD24 |
Ncbi Official Full Name |
CD24molecule |
Ncbi Organism |
Homo sapiens |
Swissprot # |
P25063 |
Fusion Tag |
His Tag |
Sequence |
Ser 27 - Gly 59 |
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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.