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HCoV-OC43 Nucleocapsid protein, His Tag

HCoV-OC43 Nucleocapsid protein, His Tag

Hersteller	ACROBiosystems
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Specific against	Coronavirus
Format	Powder
Menge	1 mg
Host	E.coli
ArtNr	NUN-V5145-1mg
Konjugat/Tag	Unconjugated, HIS
eClass 6.1	34160400
eClass 9.0	42020190
Lieferbar
Alias	Nucleocapsid protein,NP,Protein N,COVID-19
Purity	90%
Manufacturers Category	Protein / Viral Proteins
Description	HCoV-OC43 Nucleocapsid, His Tag (NUN-V5145) is expressed from E. coli cells. It contains AA Met 1 - Ile 448 (Accession # P33469-1).
Molecule	Nucleocapsid protein
Exp Region	Met 1 - Ile 448
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	50.3 kDa
Characteristics	This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 50.3 kDa. The protein migrates as 55 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin	1.0 EU per μg
Buffer	40 mM PB, 500 mM NaCl, pH7.4
Background	Nucleocapsid (N) protein is the most abundant protein found in coronavirus. CoV N protein is a highly immunogenic phosphoprotein important for viral genome replication and modulation of cell signaling pathways. It was first identified by a research team while they were screening for ADP-ribosylated proteins during coronavirus (CoV) infection (Grunewald M. E., et al. 2017, Virology; 517: 62-68). The array of diverse functional activities accommodated in N protein makes it more than a structural protein but also an interesting target in the development of antiviral therapeutics. Because of the conservation of N protein sequence and its strong immunogenicity, N protein of coronavirus is chosen as a diagnostic tool.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.