ArtNr |
NKM-SMD0901-500ug |
Hersteller |
NKMAX
|
Menge |
500 ug |
Quantity options |
100 ug
20 ug
500 ug
|
Kategorie |
|
Typ |
Proteins Recombinant |
Format |
Liquid |
Applikationen |
SDS-PAGE |
Specific against |
Human (Homo sapiens) |
Host |
E.coli |
Konjugat/Tag |
HIS |
Purity |
> 90% by SDS-PAGE |
Sequence |
MGSSHHHHHH SSGLVPRGSH MDNMSITNTP TSNDACLSIV HSLMCHRQGG ESETFAKRAI ESLVKKLKEK KDELDSLITA ITTNGAHPSK CVTIQRTLDG RLQVAGRKGF PHVIYARLWR WPDLHKNELK HVKYCQYAFD LKCDSVCVNP YHYERVVSPG IDLSGLTLQS NAPSSMMVKD EYVHDFEGQP SLSTEGHSIQ TIQHPPSNRA STETYSTPAL LAPSESNATS TA |
Citations |
Shi Y., et al. (1997) Nature. 388(6637):87-93. de Caestecker MP, et al. (1997) J Biol Chem. 272(21):13690-6. |
NCBI |
NP_005350 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Mothers against decapentaplegic homolog 4, Mothers against decapentaplegic homolog 4, SMAD family member 4, DPC4, JIP, MADH4, SMAD4, Mothers against decapentaplegic homolog 4 (Small) Mothers Against Decapentaplegic, Deleted in Pancreatic Carcinoma, Deleted in pancreatic carcinoma locus 4, Deletion target in pancreatic carcinoma 4, DPC 4, MAD mothers against decapentaplegic Drosophila homolog 4, hSMAD4, MAD homolog 4, MAD mothers against decapentaplegic homolog 4, MADH 4, Med, Medea, Mothers against DPP homolog 4, OTTHuMP00000163548, Smad 4, SMAD mothers against DPP homolog 4. |
Similar products |
SMAD4, Smad4, DPC4, JIP, MADH4, MAD homolog 4, Deletion target in pancreatic carcinoma 4, SMAD family member 4, Mothers against decapentaplegic homolog 4, Mothers against DPP homolog 4, hSMAD4, Deleted in Pancreatic Carcinoma, Deleted in pancreatic carcinoma locus 4, DPC 4, MAD mothers against decapentaplegic Drosophila homolog 4, MAD mothers against decapentaplegic homolog 4, MADH 4, Med, Medea, Mothers against decapentaplegic homolog 4 (Small) Mothers Against Decapentaplegic, OTTHuMP00000163548, Smad 4, SMAD mothers against DPP homolog 4., SMD0901-10ug, SMD0901-20ug, SMD0901-50ug, SMD0901-100ug, SMD0901-250ug, SMD0901-500ug, SMD0901-1mg, SMD0901-10, SMD0901-20, SMD0901-50, SMD0901-100, SMD0901-250, SMD0901-500, SMD0901-1 |
Lieferbar |
|
Manufacturer - Type |
Recombinant Protein |
Manufacturer - Applications |
SDS-PAGE |
Storage Conditions |
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
Molecular Weight |
62.6 kDa (572aa) |
Description |
SMAD4 belongs to the SMAD family of proteins that mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD4 promotes the binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides the function of activation required for SMAD1 or SMAD2 to stimulate transcription and may also act as a tumor suppressor. Recombinant SMAD4 protein was expressed in E. coli and purified by using conventional chromatography techniques. |
Concentration |
1mg/ml (determined by Bradford assay) |
Formulation |
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol |
Antigen Species |
Human |
Gene Category |
Cancer |
Domain |
1-552aa |
Species of Protein |
Human |
Manufacturer - Search Terms |
Smad4, Mothers against decapentaplegic homolog 4, Mothers against decapentaplegic homolog 4, SMAD family member 4, DPC4, JIP, MADH4, SMAD4, Mothers against decapentaplegic homolog 4 (Small) Mothers Against Decapentaplegic, Deleted in Pancreatic Carcinoma, Deleted in pancreatic carcinoma locus 4, Deletion target in pancreatic carcinoma 4, DPC 4, MAD mothers against decapentaplegic Drosophila homolog 4, hSMAD4, MAD homolog 4, MAD mothers against decapentaplegic homolog 4, MADH 4, Med, Medea, Mothers against DPP homolog 4, OTTHuMP00000163548, Smad 4, SMAD mothers against DPP homolog 4., SMD0901-10ug, SMD0901-20ug, SMD0901-50ug, SMD0901-100ug, SMD0901-250ug, SMD0901-500ug, SMD0901-1mg, SMD0901-10, SMD0901-20, SMD0901-50, SMD0901-100, SMD0901-250, SMD0901-500, SMD0901-1 |
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