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Recombinant human Smad4 protein

ArtNr NKM-SMD0901-500ug
Hersteller NKMAX
Menge 500 ug
Quantity options 100 ug 20 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Liquid
Applikationen SDS-PAGE
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag HIS
Purity > 90% by SDS-PAGE
Sequence MGSSHHHHHH SSGLVPRGSH MDNMSITNTP TSNDACLSIV HSLMCHRQGG ESETFAKRAI ESLVKKLKEK KDELDSLITA ITTNGAHPSK CVTIQRTLDG RLQVAGRKGF PHVIYARLWR WPDLHKNELK HVKYCQYAFD LKCDSVCVNP YHYERVVSPG IDLSGLTLQS NAPSSMMVKD EYVHDFEGQP SLSTEGHSIQ TIQHPPSNRA STETYSTPAL LAPSESNATS TA
Citations Shi Y., et al. (1997) Nature. 388(6637):87-93.
de Caestecker MP, et al. (1997) J Biol Chem. 272(21):13690-6.
NCBI NP_005350
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Mothers against decapentaplegic homolog 4, Mothers against decapentaplegic homolog 4, SMAD family member 4, DPC4, JIP, MADH4, SMAD4, Mothers against decapentaplegic homolog 4 (Small) Mothers Against Decapentaplegic, Deleted in Pancreatic Carcinoma, Deleted in pancreatic carcinoma locus 4, Deletion target in pancreatic carcinoma 4, DPC 4, MAD mothers against decapentaplegic Drosophila homolog 4, hSMAD4, MAD homolog 4, MAD mothers against decapentaplegic homolog 4, MADH 4, Med, Medea, Mothers against DPP homolog 4, OTTHuMP00000163548, Smad 4, SMAD mothers against DPP homolog 4.
Similar products SMAD4, Smad4, DPC4, JIP, MADH4, MAD homolog 4, Deletion target in pancreatic carcinoma 4, SMAD family member 4, Mothers against decapentaplegic homolog 4, Mothers against DPP homolog 4, hSMAD4, Deleted in Pancreatic Carcinoma, Deleted in pancreatic carcinoma locus 4, DPC 4, MAD mothers against decapentaplegic Drosophila homolog 4, MAD mothers against decapentaplegic homolog 4, MADH 4, Med, Medea, Mothers against decapentaplegic homolog 4 (Small) Mothers Against Decapentaplegic, OTTHuMP00000163548, Smad 4, SMAD mothers against DPP homolog 4., SMD0901-10ug, SMD0901-20ug, SMD0901-50ug, SMD0901-100ug, SMD0901-250ug, SMD0901-500ug, SMD0901-1mg, SMD0901-10, SMD0901-20, SMD0901-50, SMD0901-100, SMD0901-250, SMD0901-500, SMD0901-1
Lieferbar
Manufacturer - Type
Recombinant Protein
Manufacturer - Applications
SDS-PAGE
Storage Conditions
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Molecular Weight
62.6 kDa (572aa)
Description
SMAD4 belongs to the SMAD family of proteins that mediate signal transduction by the TGF-beta/activin/BMP-2/4 cytokine superfamily from receptor Ser/Thr protein kinases at the cell surface to the nucleus. SMAD4 promotes the binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides the function of activation required for SMAD1 or SMAD2 to stimulate transcription and may also act as a tumor suppressor. Recombinant SMAD4 protein was expressed in E. coli and purified by using conventional chromatography techniques.
Concentration
1mg/ml (determined by Bradford assay)
Formulation
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 20% glycerol
Antigen Species
Human
Gene Category
Cancer
Domain
1-552aa
Species of Protein
Human
Manufacturer - Search Terms
Smad4, Mothers against decapentaplegic homolog 4, Mothers against decapentaplegic homolog 4, SMAD family member 4, DPC4, JIP, MADH4, SMAD4, Mothers against decapentaplegic homolog 4 (Small) Mothers Against Decapentaplegic, Deleted in Pancreatic Carcinoma, Deleted in pancreatic carcinoma locus 4, Deletion target in pancreatic carcinoma 4, DPC 4, MAD mothers against decapentaplegic Drosophila homolog 4, hSMAD4, MAD homolog 4, MAD mothers against decapentaplegic homolog 4, MADH 4, Med, Medea, Mothers against DPP homolog 4, OTTHuMP00000163548, Smad 4, SMAD mothers against DPP homolog 4., SMD0901-10ug, SMD0901-20ug, SMD0901-50ug, SMD0901-100ug, SMD0901-250ug, SMD0901-500ug, SMD0901-1mg, SMD0901-10, SMD0901-20, SMD0901-50, SMD0901-100, SMD0901-250, SMD0901-500, SMD0901-1

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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