ArtNr |
NKM-FAD0801-20ug |
Hersteller |
NKMAX
|
Menge |
20ug |
Kategorie |
|
Typ |
Proteins Recombinant |
Applikationen |
SDS-PAGE |
Specific against |
other |
Konjugat/Tag |
GST-Tag |
Purity |
> 95% by SDS-PAGE |
NCBI |
NP_003815 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Fas-associated via death domain, GIG3, MORT1, MGC8528, Fas-associated via death domain, FADD, Fas-associated via death domain FADD protein, Fas TNFRSF6 associated via death domain, Fas (TNFRSF6) associated via death domain, Fas associated via death domain, Fas associating protein, Fas associating death domain containing protein, Fas associating protein with death domain GIG 3, Growth inhibiting gene 3 protein, H sapiens mRNA for mediator of receptor induced toxicity, Mediator of receptor induced toxicity, MORT 1. |
Lieferbar |
|
Antigen Species |
Human |
Bioassay Procedure |
MSPILGYWKI KGLVQPTRLL LEYLEEKYEE HLYERDEGDK WRNKKFELGL EFPNLPYYID GDVKLTQSMA IIRYIADKHN MLGGCPKERA EISMLEGAVL DIRYGVSRIA YSKDFETLKV DFLSKLPEML KMFEDRLCHK TYLNGDHVTH PDFMLYDALD VVLYMDPMCL DAFPKLVCFK KRIEAIPQID KYLKSSKYIA WPLQGWQATF GGGDHPPKSD LVPRGSMDPF LVLLHSVSSS LSSSELTELK FLCLGRVGKR KLERVQSGLD LFSMLLEQND LEPGHTELLR ELLASLRRHD LLRRVDDFEA GAAAGAAPGE EDLCAAFNVI CDNVGKDWRR LARQLKVSDT KIDSIEDRYP RNLTERVRES LRIWKNTEKE NATVAHLVGA LRSCQMNLVA DLVQEVQQAR DLQNRSGAMS PMSWNSDAST SEAS |
Concentration |
1mg/ml (determined by Bradford assay) |
Description |
FADD (Fas-associated protein with death domain) is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. This protein is implicated in survival/proliferation and cell cycle progression. FADD functions are also regulated via cellular sublocalization, protein phosphorylation, and inhibitory molecules. Recombinant human FADD, fused to GST-tag, was expressed in E. coli and purified by conventional chromatography techniques. |
Domain |
1-208aa |
Expression System |
E.coli |
Formulation |
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 20% glycerol |
Gene Category |
Cancer |
General References |
Lea Tourneur., et al:(2005) Medical Immunology. 4:1; ; Tsao, C.H., et al: (2008) J. Gen. Virol. 89; ; (PT 8), 1930-1941; ; |
Molecular Weight |
49 kDa (434aa) confirmed by MALDI-TOF |
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