ArtNr |
NKM-ATGP3117-10ug |
Hersteller |
NKMAX
|
Menge |
10ug |
Kategorie |
|
Typ |
Proteins Recombinant |
Applikationen |
SDS-PAGE |
Specific against |
other |
Konjugat/Tag |
His-Tag |
Purity |
> 90% by SDS-PAGE |
NCBI |
NP_002749 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Dual specificity mitogen-activated protein kinase kinase 6, MAPKK6, MEK6, MKK6, PRKMK6, SAPKK-3, SAPKK3 |
Lieferbar |
|
Antigen Species |
Human |
Bioassay Procedure |
MSQSKGKKRN PGLKIPKEAF EQPQTSSTPP RDLDSKACIS IGNQNFEVKA DDLEPIMELG RGAYGVVEKM RHVPSGQIMA VKRIRATVNS QEQKRLLMDL DISMRTVDCP FTVTFYGALF REGDVWICME LMDTSLDKFY KQVIDKGQTI PEDILGKIAV SIVKALEHLH SKLSVIHRDV KPSNVLINAL GQVKMCDFGI SGYLVDSVAK TIDAGCKPYM APERINPELN QKGYSVKSDI WSLGITMIEL AILRFPYDSW GTPFQQLKQV VEEPSPQLPA DKFSAEFVDF TSQCLKKNSK ERPTYPELMQ HPFFTLHESK GTDVASFVKL ILGDHHHHHH |
Concentration |
1mg/ml (determined by absorbance at 280nm) |
Description |
MAP2K6, also known as dual specificity mitogen-activated protein kinase kinase 6, is a member of the dual specificity protein kinase family, which functions as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein phosphorylates and activates p38 MAP kinase in response to inflammatory cytokines or environmental stress. As an essential component of p38 MAP kinase mediated signal transduction pathway, this gene is involved in many cellular processes such as stress-induced cell cycle arrest, transcription activation and apoptosis. Recombinant human MAP2K6, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
Domain |
1-334aa |
Endotoxin |
< 1 EU per 1ug of protein (determined by LAL method) |
Expression System |
Baculovirus |
Formulation |
Liquid in. Phosphate-Buffered Saline (pH 7.4) 20% glycerol |
Gene Category |
Cell Cycle |
General References |
Chen Z, et al (2001) J Biol Chem. 276(19):16070-5. |
Molecular Weight |
38.3 kDa (340aa) confirmed by MALDI-TOF |
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