ArtNr |
NKM-ATGP0561-500ug |
Hersteller |
NKMAX
|
Menge |
500ug |
Kategorie |
|
Typ |
Proteins Recombinant |
Applikationen |
SDS-PAGE |
Specific against |
other |
Konjugat/Tag |
His-Tag |
Purity |
> 80% by SDS-PAGE |
NCBI |
NP_115853 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
NTAL, Non-T-cell activation linker, LAT2, HSPC046, LAB, WBSCR15, WBSCR5, WSCR5, Non-T-cell activation linker LAB, Lat2, Linker for activation of B cells, Linker for activation of T cells family member 2, Membrane associated adapter molecule, Non T cell activation linker, WBSCR 5, Wbscr15, Williams Beuren syndrome chromosome region 15, Williams Beuren syndrome chromosome region 5 |
Lieferbar |
|
Antigen Species |
Human |
Concentration |
0.25mg/ml (determined by Bradford assay) |
Description |
NTAL (non-T cell activation linker), as known as LAT2, is transmembrane adaptor protein (TRAP) associated with glycolipid-enriched membrane fractions (GEM or lipid rafts). This protein is primarily expressed in spleen and hematopoietic cells, such as B cells, mast cells, NK cells, and monocytes, but not resting T cells. Defects in NTAL may be a cause of certain cardiovascular and musculo-skeletal abnormalities observed in Williams-Beuren syndrome (WBS). Recombinant human NTAL, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. |
Expression System |
E.coli |
Formulation |
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol |
Gene Category |
Immunology |
General References |
Naumann M., et al. (2010) Cell Signal. 22(3):395-403.; ; Gilfillan AM., et al. (2008). Int J Biochem Cell Biol. 39(5): 868-873.; ; |
Molecular Weight |
26.2 kDa (238aa) confirmed by MALDI-TOF |
Storage |
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
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