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Cynomolgus LILRB4/CD85k/ILT3 Protein (LIL-CM1B4)

ArtNr LIL-CM1B4-100UG
Hersteller KactusBio
Menge 100 ug
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against Monkey
Host HEK293
Konjugat/Tag HIS
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Formula Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization.
Sequence Gln22-Glu259
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias HM18; ILT3; ILT-3; LILRB4; LIR5; CD85K
Lieferbar
Description
Recombinant Cynomolgus LILRB4/CD85k/ILT3 Protein Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln22-Glu259.
Background
LILRB4, also known as CD85k and LIR-5, ILT3,   is an approximately 60 kDa transmembrane glycoprotein that negatively regulates immune cell activation. Mature human ILT3 consists of a 238 amino acid (aa) extracellular domain with two Ig-like domains, a 21 aa transmembrane segment, and a 168 aa cytoplasmic domain with 3 immunoreceptor tyrosine-based inhibitory motifs (ITIM).LILRB4 is receptor for class I MHC antigens. Recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles.
Manufacturers Product Type
Recombinant Protein
Endotoxin
Less than 1EU per μg by the LAL method.
Molecular Weight
The protein has a predicted MW of 27.2 kDa. Due to glycosylation, the protein migrates to 35-42 kDa based on Tris-Bis PAGE result.
Stability and Storage
-20 to -80°C for 12 months as supplied from date of receipt.; -80°C for 3-6 months after reconstitution.; 2-8°C for 2-7 days after reconstitution.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Tag Information
C-His
Formulation
Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 5% trehalose is added as protectant before lyophilization.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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Lieferung vsl. bis 27.09.2024 

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