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Cynomolgus LILRB2 / CD85d / ILT4 Protein, His Tag Europäischer Partner

ArtNr LI2-C52H3-1mg
Hersteller ACROBiosystems
Menge 1 mg
Quantity options 100 ug 1 mg
Kategorie
Typ Proteins Recombinant
Format Powder
Specific against Monkey (Cynomolgus, Simian)
Host HEK293
Konjugat/Tag HIS, Unconjugated
Purity 95%
NCBI BAE87348.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias LILRB2,ILT4,LIR2,MIR10,CD85d
Versandbedingung Raumtemperatur
Lieferbar
Specificity Cynomolgus
Manufacturer - Category
Protein / Immune Checkpoint Proteins
Manufacturer - Conjugate / Tag
C-10×His, Unconjugated
Manufacturer - Species
Cynomolgus
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
48.5 kDa
Description
Cynomolgus LILRB2, His Tag (LI2-C52H3) is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Leu 448 (Accession # BAE87348.1).
Background
Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2) is also known as CD85 antigen-like family member D (CD85d), Immunoglobulin-like transcript 4 (ILT-4), Monocyte / macrophage immunoglobulin-like receptor 10 (MIR-10), which is a member of the the subfamily B class of LIR receptors. LILRB2 is receptor for class I MHC antigens. LILRB2 recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB2 competes with CD8A for binding to class I MHC antigens. LILRB2 / CD85d inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
Molecule
LILRB2
Exp Region
Gly 24 - Leu 448
Characteristics
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 48.5 kDa. The protein migrates as 60-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state;
● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 mg
Lieferbar: In stock
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