ArtNr |
LG9-H5244-50ug |
Hersteller |
ACROBiosystems
|
Menge |
50 ug |
Quantity options |
1 mg
50 ug
|
Kategorie |
|
Typ |
Proteins Recombinant |
Format |
Powder |
Specific against |
Human (Homo sapiens) |
Host |
HEK293 |
Konjugat/Tag |
HIS, Unconjugated |
Purity |
95% |
Citations |
(1) Tuereci O., et al., 1997, J. Biol. Chem. 272:6416-6422. (2) Dai S.Y., et al.,2005, J. Immunol. 175:2974-2981. |
NCBI |
BAA31542.1 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
Galectin-9,LGALS9,Ecalectin |
Versandbedingung |
Raumtemperatur |
Lieferbar |
|
Manufacturer - Category |
Protein / Immune Checkpoint Proteins |
Manufacturer - Conjugate / Tag |
N-6×His, Unconjugated |
Shipping Temperature |
RT |
Storage Conditions |
-20°C |
Molecular Weight |
36.6 kDa |
Description |
Human Galectin-9, His Tag (LG9-H5244) is expressed from human 293 cells (HEK293). It contains AA Ala 2 - Thr 323 (Accession # O00182-2). |
Background |
Galectin-9 (LGALS9) is also known as tumor antigen HOM-HD-21 and ecalectin. Galectins are a family of proteins defined by their binding specificity for β-galactoside sugars, such as N-acetyllactosamine (Galβ1-3GlcNAc or Galβ1-4GlcNAc), which can be bound to proteins by either N-linked or O-linked glycosylation. As for Galectin-9, it has high affinity for the Forssman pentasaccharide, and it is also the ligand for HAVCR2/TIM3. Forthermore, Galectin-9 stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth. |
Molecule |
Galectin-9 |
Exp Region |
Ala 2 - Thr 323 |
Characteristics |
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 36.6 kDa. The protein migrates as 45-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin |
1.0 EU per μg |
Buffer |
20 mM MOPS, 50 mM NaCl, pH7.4 |
Stability |
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution.
For long term storage, the product should be stored at lyophilized state at -20°C or lower. |
Protectant |
trehalose |
Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.
Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.