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Human Galectin-9 / LGALS9 Protein, His Tag Europäischer Partner

ArtNr LG9-H5244-1mg
Hersteller ACROBiosystems
Menge 1 mg
Quantity options 1 mg 50 ug
Kategorie
Typ Proteins Recombinant
Format Powder
Specific against Human (Homo sapiens)
Host HEK293
Konjugat/Tag HIS, Unconjugated
Purity 95%
Citations (1) Tuereci O., et al., 1997, J. Biol. Chem. 272:6416-6422. (2) Dai S.Y., et al.,2005, J. Immunol. 175:2974-2981.
NCBI BAA31542.1
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Galectin-9,LGALS9,Ecalectin
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Protein / Immune Checkpoint Proteins
Manufacturer - Conjugate / Tag
N-6×His, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
36.6 kDa
Description
Human Galectin-9, His Tag (LG9-H5244) is expressed from human 293 cells (HEK293). It contains AA Ala 2 - Thr 323 (Accession # O00182-2).
Background
Galectin-9 (LGALS9) is also known as tumor antigen HOM-HD-21 and ecalectin. Galectins are a family of proteins defined by their binding specificity for β-galactoside sugars, such as N-acetyllactosamine (Galβ1-3GlcNAc or Galβ1-4GlcNAc), which can be bound to proteins by either N-linked or O-linked glycosylation. As for Galectin-9, it has high affinity for the Forssman pentasaccharide, and it is also the ligand for HAVCR2/TIM3. Forthermore, Galectin-9 stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth.
Molecule
Galectin-9
Exp Region
Ala 2 - Thr 323
Characteristics
This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 36.6 kDa. The protein migrates as 45-55 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
20 mM MOPS, 50 mM NaCl, pH7.4
Stability
● -20°C to -70°C for 12 months in lyophilized state;
● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 mg
Lieferbar: In stock
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