Recombinant Human Cathepsin L

A cathepsin is a cysteine or aspartic protease, a type of protein that breaks apart other proteins, found in many types of cells including those in all animals. There are approximately a dozen members of this family, which are distinguished by their structure and which proteins they cleave. Most of the members become activated at the low pH found in lysosomes. Thus, the activity of this family lies almost entirely within those organelles. Cathepsins have a vital role in mammalian cellular turnover, e.g. bone resorption. They degrade polypeptides and are distinguished by their substrate specificites.

The cytokine is supplied frozen in 50 mM sodium acetate, 0.4 M NaCl, pH 5.0.

The frozen protein is stable for 6 months when kept a -20°C to -70°C in a manual defrost freezer. Avoid repeat freeze thaw cycles..