Recombinant Human VEGFA Protein, MAT Tag

VEGFA

P15692

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Protein A/G

VEGFA is apolypeptide growth factor and a member of the platelet-derived growth factorfamily. It is a specific mitogen for vascular endothelial cells and a strongangiogenic factor in vivo. Two high-affinity tyrosine kinase receptors forVEGF121 have been identified, VEGFA (FLT-1), and VEGFR-2 (KDR).Consistent with the endothelial cell-specific action of VEGF121, expressionof both receptor genes has been found predominantly but not exclusively on endothelialcells. Expression of VEGFA was also found on human monocytes, neutrophils(PMNs), bovine brain pericytes and villous and extravillous trophoblasts.

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