Recombinant Human CD40 Protein, His Tag

CD40

P25942

< 1.0 EU per ug of the protein as determined by the LAL method.

Protein A/G

CD4 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD4L) on TH cells to CD4 activates antigen presenting cells and induces a variety of downstream effects. The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been found to be essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. AT-hook transcription factor AKNA is reported to coordinately regulate the expression of this receptor and its ligand, which may be important for homotypic cell interactions.

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