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Mouse Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein (ITG-MM1V6)

Mouse Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein (ITG-MM1V6)

ArtNr	ITG-MM1V6-500UG
Hersteller	KactusBio
Menge	500 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Lyophilized
Specific against	Mouse
Host	HEK293
Konjugat/Tag	HIS
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Formula	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Sequence	Phe31-Val988(ITGAV)acidic tail & Gly22-Asn706(ITGB6)basic tail
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	ITGAV&ITGB6；Integrin alpha V beta 6
Lieferbar
Description	Recombinant Mouse Integrin alpha V beta 6 (ITGAV&ITGB6) Heterodimer Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Phe31-Val988(ITGAV) acidic tail&Gly22-Asn706(ITGB6) basic tail.
Background	ITGAV&ITGB6 is a receptor for fibronectin and cytotactin. It recognizes the sequence R-G-D in its ligands. Internalisation of integrin alpha-V/beta-6 via clathrin-mediated endocytosis promotes carcinoma cell invasion. ITGAV&ITGB6 acts as a receptor for fibrillin-1 (FBN1) and mediates R-G-D-dependent cell adhesion to FBN1.
Manufacturers Product Type	Recombinant Protein
Endotoxin	Less than 1EU per μg by the LAL method.
Molecular Weight	The protein has a predicted MW of 111.6 kDa (ITGAV)&79.2 kDa (ITGB6). Due to glycosylation, the protein migrates to 90-140 kDa based on Tris-Bis PAGE result.
Stability and Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3-6 months after reconstitution.；2-8°C for 2-7 days after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Tag Information	C-His
Formulation	Lyophilized from 0.22μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

ITG-MM1V6-500UG-datasheet.pdf

ITG-MM1V6-500UG-safety-datasheet.pdf