« Zurück
Home /
Human Integrin alpha 9 beta 1 (ITGA9&ITGB1) Heterodimer Protein, His Tag&Tag Free

Human Integrin alpha 9 beta 1 (ITGA9&ITGB1) Heterodimer Protein, His Tag&Tag Free

ArtNr	IT1-H52W4-100ug
Hersteller	ACROBiosystems
Menge	100 ug
Quantity options	100 ug 250 ug x 4
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Powder
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	Unconjugated, HIS
Purity	95%
Citations	(1) Takada Y., et al. 2007, Genome Biol., 8(5), 215. (2) Luo BH., et al. 2007, Annu Rev Immunol., 25, 619-47. (3) Yokosaki Y., et al. 1999, J Biol Chem., 274(51), 36328-34.
NCBI	NP_002198.2 (ITGA9) , NP_002202.2 (ITGB1)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Integrin alpha 9 beta 1,ITGA9 & ITGB1
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Protein / Bio-Markers & CD Antigens
Manufacturer - Conjugate / Tag	Unconjugated, C-10xHis \| Native
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	111.1 kDa (ITGA9) & 82.7 kDa (ITGB1)
Description	Human ITGA9&ITGB1 Heterodimer Protein, His Tag&Tag Free (IT1-H52W4) is expressed from human 293 cells (HEK293). It contains AA Tyr 30 - Trp 981 (ITGA9) & Gln 21 - Asp 728 (ITGB1) (Accession # Q13797-1 (ITGA9) & P05556-1 (ITGB1)).
Background	Integrin alpha 9 beta 1 is one of twelve integrin family adhesion receptors that share the beta 1 (CD29) subunit. It is the non-covalent heterodimer of 150 kDa alpha 9 and 130 kDa beta 1 type I transmembrane glycoprotein subunits. The integrin alpha 9 beta 1 mediates cell adhesion to tenascin-C and VCAM-1 by binding to sequences distinct from the common integrin-recognition sequence, arginine-glycine-aspartic acid (RGD). A thrombin-cleaved NH(2)-terminal fragment of osteopontin containing the RGD sequence has recently been shown to also be a ligand for integrin alpha 9 beta 1.
Molecule	Integrin alpha 9 beta 1
Exp Region	Tyr 30 - Trp 981 (ITGA9) & Gln 21 - Asp 728 (ITGB1)
Characteristics	Human ITGA9&ITGB1 Heterodimer Protein, His Tag&Tag Free, produced by co-expression of ITGA9 and ITGB1, has a calculated MW of 111.1 kDa (ITGA9) and 82.7 kDa (ITGB1). Subunit ITGA9 is fused with an acidic tail at the C-terminus and followed by a polyhistidine tag and subunit ITGB1 contains no tag but a basic tail at the C-terminus. The reducing (NR) protein migrates as 210-240 kDa respectively due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	50 mM Tris, 150 mM NaCl, pH7.5
Stability	● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution.For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

IT1-H52W4-100ug-datasheet.pdf

IT1-H52W4-100ug-safety-datasheet.pdf