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Biotinylated Human IL-3 R alpha / CD123 Protein, His,Avitag™, premium grade

Biotinylated Human IL-3 R alpha / CD123 Protein, His,Avitag™, premium grade

ArtNr	ILA-H82H5-25ug
Hersteller	ACROBiosystems
Menge	25 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Powder
Specific against	Human
Host	HEK293
Konjugat/Tag	Biotin, HIS, Avi
Purity	90%
Citations	(1) Mardiros A., et al. 2013, Blood., 122(18), 3138-48. (2) Rapoport AP., et al. 1996, Blood., 87(1), 112-22. (3) Klöß S., et al. 1996, Hum Gene Ther., 28(10), 897-913.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IL3R,IL3RA,IL-3Ra,IL-3R-alpha,IL3RAY,IL3RX,IL3RY,CD123 antigen,CD123,hIL3Ra,hIL-3Ra,MGC34174,IL-3 R alpha
Lieferbar
Manufacturers Category	Protein / MABSol® Biotin Labeled Proteins
Description	Biotinylated Human IL-3 R alpha Protein, His, Avitag, premium grade (ILA-H82H5) is expressed from human 293 cells (HEK293). It contains AA Thr 19 - Arg 305 (Accession # P26951-1).
Molecule	IL-3 R alpha
Exp Region	Thr 19 - Arg 305
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	36.7 kDa
Characteristics	This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 36.7 kDa. The protein migrates as 57 kDa±3 kDa under reducing (R) condition, and 54 kDa±3 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under non-reducing (NR) condition (SDS-PAGE) due to glycosylation.
Endotoxin	0.01 EU per μg
Buffer	PBS, pH7.4
Background	Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 25 ug

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Lieferung vsl. bis 27.09.2024

Express-Lieferung: 3 Tage sparen

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