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Cynomolgus IL-31 Protein, His Tag

Cynomolgus IL-31 Protein, His Tag

Hersteller	ACROBiosystems
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Specific against	Monkey
Format	Powder
Menge	1 mg
Host	HEK293
ArtNr	IL1-C5245-1mg
Konjugat/Tag	Unconjugated, HIS
eClass 6.1	34160400
eClass 9.0	42020190
Lieferbar
Alias	IL-31,IL31,Interleukin-31
Purity	90%
Manufacturers Category	Protein / Cytokines&Growth Factors
Description	Cynomolgus IL-31, His Tag (IL1-C5245) is expressed from human 293 cells (HEK293). It contains AA Leu 27 - Thr 163 (Accession # G7PJ78-1).
Molecule	IL-31
Exp Region	Leu 27 - Thr 163
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	17.3 kDa
Characteristics	This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 17.3 kDa. The protein migrates as 20-25 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Background	IL-31 is an inflammatory cytokine that helps trigger cell-mediated immunity against pathogens. Activates STAT3 and possibly STAT1 and STAT5 through the IL31 heterodimeric receptor composed of IL31RA and OSMR. It has also been identified as a major player in a number of chronic inflammatory diseases, including atopic dermatitis. May function in skin immunity. IL-31 is produced by a variety of cells, namely type 2 helper (TH2) T-cells. IL-31 sends signals through a receptor complex made of IL-31RA and oncostatin M receptor β (OSMRβ) expressed in immune and epithelial cells. These signals activate three pathways: ERK1/2 MAP kinase, PI3K/AKT, and JAK1/2 signaling pathways.

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Menge: 1 mg

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Lieferung vsl. bis 26.07.2024

Express-Lieferung: 3 Tage sparen

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