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Rat GITR / TNFRSF18 Protein, His Tag

Rat GITR / TNFRSF18 Protein, His Tag

ArtNr	GIR-R5222-100ug
Hersteller	ACROBiosystems
Menge	100 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Powder
Specific against	Rat
Host	HEK293
Konjugat/Tag	Unconjugated, HIS
Purity	95%
Citations	(1) Gurney A.L., et al., 1999, Curr. Biol. 9:215-218. (2) Park MS., et al., 2007, Yonsei Med J 48 (5): 839-46.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	AITR,GITR,TNFRSF18,CD357
Lieferbar
Manufacturers Category	Protein / Immune Checkpoint Proteins
Description	Rat GITR, His Tag (GIR-R5222) is expressed from human 293 cells (HEK293). It contains AA Gln 20 - Lys 121 (Accession # Q5M835).
Molecule	GITR
Exp Region	Gln 20 - Lys 121
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	12.3 kDa
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 12.3 kDa. The protein migrates as 21 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Background	Glucocorticoid-induced TNFR-related protein (GITR) is also known as Tumor necrosis factor receptor superfamily member 18 (TNFRSF18), activation-inducible TNFR family receptor (AITR), CD antigen CD357, which is a member of the tumor necrosis factor receptor (TNF-R) superfamily. GITR is receptor for TNFSF18, which seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR also mediated NF-kappa-B activation via the TRAF2/NIK pathway.

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Menge: 100 ug

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Lieferung vsl. bis 16.08.2024

Express-Lieferung: 3 Tage sparen

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