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Biotinylated Human FcRn Protein (FRN-HM401B)

ArtNr FRN-HM401B-500UG
Hersteller KactusBio
Menge 500 ug
Quantity options 100 ug 500 ug
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against Human
Host HEK293
Konjugat/Tag HIS, Avi
Purity > 95% as determined by Bis-Tris PAGE; > 95% as determined by HPLC
Sequence Ala24-Ser297(FCGRT) & Ile21-Met119(B2M)
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias FcRn alpha chain, FCGRT, FCRN, FCGRT&B2M
Lieferbar
Manufacturer - Product Type
Recombinant Protein
Description
Recombinant Biotinylated Human FcRn Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Ala24-Ser297(FCGRT)&Ile21-Met119(B2M).
Background
The neonatal Fc receptor (FCRN) is an approximately 45 kDa transmembrane glycoprotein with structural homology to MHC class I proteins. It is widely expressed in endothelial and epithelial cells and plays an important role in IgG homeostasis and antigen presentation by dendritic cells.FCGRT & B2M heterodimer protein (FcRn complex) consist of two subunits: p51, and p14 , and forms an MHC class I-like heterodimer.
Endotoxin
Less than 1 EU per μg by the LAL method.
Molecular Weight
The protein has a predicted MW of 46.5 kDa. Due to glycosylation, the protein migrates to 48-55 kDa based on Bis-Tris PAGE result.
Target
FcRn
Manufacturer - Tag
C-His-Avi
Stability and Storage
-20 to -80°C for 12 months as supplied from date of receipt; -80°C for 3-6 months after reconstitution; 2-8°C for 2-7 days after reconstitution; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 μm filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 μg/ml is recommended. Dissolve the lyophilized protein in distilled water.
Biotinylated
yes

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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