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Mouse Fc gamma RIV / CD16-2 Protein, His Tag (MALS verified)

Mouse Fc gamma RIV / CD16-2 Protein, His Tag (MALS verified)

Hersteller	ACROBiosystems
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Specific against	Mouse
Format	Powder
Menge	100 ug
Host	HEK293
ArtNr	FC4-M52H3-100ug
Konjugat/Tag	Unconjugated, HIS
eClass 6.1	34160400
eClass 9.0	42020190
Lieferbar
Alias	Fc gamma RIV,CD16-2,Fcgr4
Purity	90%
Manufacturers Category	Protein / MABSol® Fc Receptors
Description	Mouse CD16-2, His Tag (FC4-M52H3) is expressed from human 293 cells (HEK293). It contains AA Gly 21 - Gln 203 (Accession # A0A0B4J1G0-1).
Molecule	Fc gamma RIV / CD16-2
Exp Region	Gly 21 - Gln 203
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 12 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	22.8 kDa
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 22.8 kDa. The protein migrates as 28-35 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Background	FcgR4(Low affinity immunoglobulin gamma Fc region receptor IV) is also known as CD16-2, FcgammaRIV, receptor for the Fc region of immunoglobulin gamma . Also acts as a receptor for the Fc region of immunoglobulin epsilon . Binds with intermediate affinity to both IgG2a and IgG2b . Does not display binding to IgG1 or IgG3. Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a. Binds with low affinity to both the a and b allotypes of IgE. Has also been shown to bind to IgE allotype a only but not to allotype b. Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of proinflammatory cytokines and the late phase of cutaneous allergic reactions

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Einfache Bestellung Periodische Bestellung

Menge: 100 ug

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Lieferung vsl. bis 26.07.2024

Express-Lieferung: 3 Tage sparen

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