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Human HBEGF Protein, hFc Tag

ArtNr DIM-PME100686-10ug
Hersteller DIMA Biotechnology
Menge 10ug
Kategorie
Typ Proteins Recombinant
Specific against other
Konjugat/Tag C-Human Fc tag
Purity The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias DTR; DTS; DTSF; HEGFL
Lieferbar
Background
Growth factor that mediates its effects via EGFR, ERBB2 and ERBB4. Required for normal cardiac valve formation and normal heart function. Promotes smooth muscle cell proliferation. May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts, but not endothelial cells. It is able to bind EGF receptor/EGFR with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.[UniProtKB/Swiss-Prot Function]
Description
Recombinant Human HBEGF with C-terminal human Fc tag
Expression Host
HEK293
Formulation & Reconstitution
Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8% trehalose is added as protectants before lyophilization. Please see Certificate of Analysis for specific instructions.
Molecular Weight
The protein has a predicted molecular mass of 41.9 kDa after removal of the signal peptide. The apparent molecular mass of HBEGF-hFc is approximately 35-55 kDa due to glycosylation.
Storage
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized proteins are shipped at ambient temperature.
Usage
Research use only

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10ug
Lieferbar: In stock
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