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Recombinant Mouse Apolipoprotein E(Apoe)

Recombinant Mouse Apolipoprotein E(Apoe)

ArtNr	CSB-YP001936MO-20
Hersteller	Cusabio
Menge	20ug
Kategorie	Neuroscience Metabolism Glucose Homeostasis Cholesterol & Lipid Metabolism Aging & Neurological Disorders Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Liquid or Lyophilized powder
Specific against	Mouse
Host	Yeast
Purity	Greater than 90% as determined by SDS-PAGE.
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
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Research Areas	Others
Target / Protein	Apoe
Biologically Active	Not Test
Expression System	Yeast
Species of origin	Mus musculus (Mouse)
Uniprot ID	P08226
AA Sequence	EGEPEVTDQLEWQSNQPWEQALNRFWDYLRWVQTL SDQVQEELQSSQVTQELTALMEDTMTEVKAYKKEL EEQLGPVAEETRARLGKEVQAAQARLGADMEDLRN RLGQYRNEVHTMLGQSTEEIRARLSTHLRKMRKRL MRDAEDLQKRLAVYKAGAREGAERGVSAIRERLGP LVEQGRQRTANLGAGAAQPLRDRAQAFGDRIRGRL EEVGNQARDRLEEVREHMEEVRSKMEEQTQQIRLQ AEIFQARLKGWFEPIVEDMHRQWANLMEKIQASVA TNPIITPVAQENQ
Tag Info	N-terminal 6xHis-tagged
Expression Region	19-311aa
Protein Length	Full Length of Mature Protein
MW	36 kDa
Relevance	Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron rnant) of hepatic tissues.
Reference	Mass spectral analysis of the apolipoproteins on mouse high density lipoproteins. Detection of post-translational modifications.Puppione D.L., Yam L.M., Bassilian S., Souda P., Castellani L.W., Schumaker V.N., Whitelegge J.P.Biochim. Biophys. Acta 1764:1363-1371(2006)
Purity	Greater than 90% as determined by SDS-PAGE.
Form	Liquid or Lyophilized powder
Buffer	If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20C/-80C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Storage	The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes	Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function	Mediates the binding, internalization, and catabolism of lipoprotein particles. It can serve as a ligand for the LDL (apo B/E) receptor and for the specific apo-E receptor (chylomicron remnant) of hepatic tissues.
Subcellular Location	Secreted
Protein Families	Apolipoprotein A1/A4/E family
Tissue Specificity	Secreted in plasma.
Tag Information	N-terminal 6xHis-tagged

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