ArtNr |
CSB-EP818263HUa0-20 |
Hersteller |
Cusabio
|
Menge |
20ug |
Quantity options |
1mg
10ug
100ug
20ug
200ug
50ug
500ug
|
Kategorie |
|
Typ |
Proteins Recombinant |
Format |
Liquid or Lyophilized powder |
Specific against |
Human |
Purity |
Greater than 85% as determined by SDS-PAGE. |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Lieferbar |
|
Research Areas |
Others |
Target / Protein |
TMEFF1 |
Biologically Active |
Not Test |
Expression System |
E.coli |
Species of origin |
Homo sapiens (Human) |
Uniprot ID |
Q8IYR6 |
AA Sequence |
SNQPPGGGGGSGGDCPGGKGKSINCSELNVRESDV RVCDESSCKYGGVCKEDGDGLKCACQFQCHTNYIP VCGSNGDTYQNECFLRRAACKHQKEITVIARGPCY SDNGSGSGEGEEEGSGAEVHRKHSKCGPCKYKAEC DEDAENVGCVCNIDCSGYSFNPVCASDGSSYNNPC FVREASCIKQEQIDIRHLGHCTDTDDTSLLGKKDD GLQYRPDVKDASDQREDVYIGNHMPCPENLNGYCI HGKCEFIYSTQKASCRCESGYTGQHCEKTDFSILY VVPSRQKLTHV |
Tag Info |
N-terminal 6xHis-tagged |
Expression Region |
40-330aa |
Protein Length |
Partial |
MW |
35.5 kDa |
Alternative Name(s) |
H7365 Transmembrane protein with EGF-like and one follistatin-like domain C9orf2 |
Relevance |
May inhibit NODAL and BMP signaling during neural patterning. May be a tumor suppressor in brain cancers. |
Reference |
A novel transmembrane protein with epidermal growth factor and follistatin domains expressed in the hypothalamo-hypophysial axis of Xenopus laevis. Eib D.W., Martens G.J.M. J. Neurochem. 67:1047-1055(1996) |
Purity |
Greater than 85% as determined by SDS-PAGE. |
Form |
Liquid or Lyophilized powder |
Buffer |
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0. |
Reconstitution |
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20C/-80C. Our default final concentration of glycerol is 50%. Customers could use it as reference. |
Storage |
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C. |
Notes |
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week. |
Function |
May inhibit NODAL and BMP signaling during neural patterning (By similarity). May be a tumor suppressor in brain cancers. |
Subcellular Location |
Cell membrane, Single-pass type I membrane protein |
Protein Families |
Tomoregulin family |
Tissue Specificity |
Expressed predominantly in brain, and at lower levels in heart, placenta and skeletal muscle. Down-regulated in brain tumors as compared to control brain tissues. |
Tag Information |
N-terminal 6xHis-tagged |
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