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Recombinant Rat Dipeptidyl aminopeptidase-like protein 6(Dpp6),partial

ArtNr CSB-EP007140RA-20
Hersteller Cusabio
Menge 20ug
Quantity options 1mg 10ug 100ug 20ug 200ug 50ug 500ug
Kategorie
Typ Proteins Recombinant
Format Liquid or Lyophilized powder
Specific against other
Host E.coli
Purity Greater than 90% as determined by SDS-PAGE.
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
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Research Areas
Others
Uniprot ID
P46101
Gene Names
DPP6
Organism
Rattus norvegicus (Rat)
AA Sequence
LTPAEDTSLSQKKKVTVEDLFSEDFKIHDPEAKWI SDKEFIYRERKGSVILRNVETNNSTVLIEGKKIES LRAIRYEISPDKEYALFSYNVEPVYQHSHTGYYVL SKIPHGDPQSLDPPEVSNAKLQYAGWGPKGQQLIF IFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDW LYEEEILKSHIAHWWSPDGTRLAYATINDSRVPLM ELPTYTGSVYPTVKPYHYPKAGSENPSISLHVIGL NGPTHDLEMMPPDDPRMREYYITMVKWATSTKVAV TWLNRAQNVSILTLCDATTGVCTKKHEDESEAWLH RQNEEPVFSKDGRKFFFVRAIPQGGRGKFYHITVS SSQPNSSNDNIQSITSGDWDVTEILTYDEKRNKLY FLSTEDLPRRRHLYSANTVDDFNRQCLSCDLVENC TYVSASFSHNMDFFLLKCEGPGVPTVTVHNTTDKR RMFDLEANEQVQKAIYDRQMPKIEYRKIEVEDYSL PMQILKPATFTDTAHYPLLLVVDGTPGSQSVSERF EVTWETVLVSSHGAVVVKCDGRGSGFQGTKLLHEV RRRLGFLEEKDQMEAVRTMLKEQYIDKTRVAVFGK DYGGYLSTYILPAKGENQGQTFTCGSALSPITDFK LYASAFSERYLGLHGLDNRAYEMTKLAHRVSALED QQFLIIHATADEKIHFQHTAELITQLIKGKANYSL QIYPDESHYFHSVALKQHLYRSIIGFFVECFRIQD KLPTATAKEDEEED
Expression Region
111-859aa
Sequence Info
Extracellular Domain
Source
E.coli
Tag Info
N-terminal 6xHis-tagged
MW
89.6 kDa
Alternative Name(s)
DPPXDipeptidyl aminopeptidase-related proteinDipeptidyl peptidase 6Dipeptidyl peptidase IV-like proteinDipeptidyl peptidase VI ; DPP VI
Relevance
Promotes cell surface expression of the potassium channel KCND2 . Modulates the activity and gating characteristics of the potassium channel KCND2 . Has no dipeptidyl aminopeptidase activity .
Reference
The dipeptidyl-peptidase-like protein DPP6 determines the unitary conductance of neuronal Kv4.2 channels.Kaulin Y.A., De Santiago-Castillo J.A., Rocha C.A., Nadal M.S., Rudy B., Covarrubias M.J. Neurosci. 29:3242-3251(2009)
Purity
Greater than 90% as determined by SDS-PAGE.
Form
Liquid or Lyophilized powder
Buffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol.
If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.
Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20C/-80C. Our default final concentration of glycerol is 50%. Customers could use it as reference.
Storage
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20C/-80C. The shelf life of lyophilized form is 12 months at -20C/-80C.
Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4C for up to one week.
Function
Promotes cell surface expression of the potassium channel KCND2
Subcellular Location
Cell membrane, Single-pass type II membrane protein
Protein Families
Peptidase S9B family
Tissue Specificity
Detected in brain cortex, hippocampus, thalamus and cerebellum granule cells (at protein level) (PubMed:16123112). Isoform DPPX-S is expressed in brain and some peripheral tissues including kidney, ovary, and testis; in contrast isoform DPPX-L is expressed almost exclusively in brain.
Tag Information
N-terminal 6xHis-tagged

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 20ug
Lieferbar: In stock
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