Vergleich

Human CD24 Protein, His Tag (Nanoparticle) Europäischer Partner

ArtNr CD4-H52H5-1mg
Hersteller ACROBiosystems
Menge 1 mg
Kategorie
Typ Proteins Recombinant
Format Powder
Specific against Human
Host HEK293
Konjugat/Tag Unconjugated, HIS
Purity 90%
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Lieferbar
Manufacturers Category
Protein / Other Recombinant Proteins
Description
Human CD24 Protein, His Tag (CD4-H52H5) is expressed from human 293 cells (HEK293). It contains AA Ser 27 - Gly 59 (Accession # P25063-1).
Molecule
CD24
Exp Region
Ser 27 - Gly 59
Storage
-20℃
Shipping
RT
Stability
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight
34.3 kDa
Characteristics
Human CD24 Protein, His Tag is designed and expressed as nanoparticles of approximately 25 nm diameter by displaying CD24 ECD in native conformation. The nanoparticles each was coated with an average of 180 CD24 ECD.
The nanoparticle technology allows directional and high-density display of human CD24 on the surface of nanoparticles, thus greatly enhances the immune response in vivo to otherwise poorly immunogenic epitopes.
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 34.3 kDa. The protein migrates as 43-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
0.5 EU per μg
Buffer
PBS with glycine and sodium citrate, pH8.0
Background
CD24 may have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity.

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 mg
Lieferbar: In stock
lieferbar

Lieferung vsl. bis 23.08.2024 

Vergleichen

Auf den Wunschzettel

Angebot anfordern

Lieferzeit anfragen

Technische Frage stellen

Bulk-Anfrage stellen

Fragen zum Produkt?
 
Schließen