ArtNr |
BTA-M5253-100ug |
Hersteller |
ACROBiosystems
|
Menge |
100 ug |
Kategorie |
|
Typ |
Proteins Recombinant |
Format |
Powder |
Specific against |
Mouse |
Host |
HEK293 |
Konjugat/Tag |
Unconjugated, Fc |
Purity |
95% |
Citations |
(1) Watanabe N., et al., 2003, Nat. Immunol. 4:670-679. (2) Gavrieli M., et al., 2003, Biochem. Biophys. Res. Commun. 312:1236-1243. (3) Sedy J.R., et al., 2005, Nat. Immunol. 6:90-98. |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
BTLA,CD272 |
Lieferbar |
|
Manufacturers Category |
Protein / Immune Checkpoint Proteins |
Description |
Mouse BTLA, Fc Tag (BTA-M5253) is expressed from human 293 cells (HEK293). It contains AA Glu 30 - Gly 176 (Accession # Q32MV9). |
Molecule |
BTLA |
Exp Region |
Glu 30 - Gly 176 |
Storage |
-20℃ |
Shipping |
RT |
Stability |
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution.
For long term storage, the product should be stored at lyophilized state at -20°C or lower. |
Molecular Weight |
42.8 kDa |
Characteristics |
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 42.8 kDa. The protein migrates as 55-66 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin |
1.0 EU per μg |
Buffer |
Tris with Glycine, Arginine and NaCl, pH7.5 |
Background |
B- and T-lymphocyte attenuator (BTLA) is also known as B- and T-lymphocyte-associated protein, CD antigen CD272. BTLA contains one Ig-like V-type (immunoglobulin-like) domain. As a lymphocyte inhibitory receptor, BTLA / CD272 inhibits lymphocytes during immune response. BTLA / CD272 can interact with tyrosine phosphatases PTPN6/SHP-1 and PTPN11/SHP-2, and interact with TNFRSF14/HVEM. |
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