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Human BMP-2 Protein, premium grade Europäischer Partner

ArtNr BM2-H4117-1mg
Hersteller ACROBiosystems
Menge 1 mg
Quantity options 1 mg 200 ug 20 ug
Kategorie
Typ Proteins Recombinant
Format Solid
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag Unconjugated
Purity 95%
Citations (1) Lai, T.H. et al., (2008) Prostate. 68: 1341-1353. (2) Kruithof BP,et al. Genesis. 2011 Apr 18. doi: 10.1002/dvg.20757. (3) Grgurevic L, et al. Biochem Biophys Res Commun. 2011 Apr 29;408(1):25-31.
NCBI NP_001191
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias BMP2,BMP2A
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Category
Protein / Cytokines&Growth Factors
Manufacturer - Conjugate / Tag
Native, Unconjugated
Shipping Temperature
RT
Storage Conditions
-20°C
Molecular Weight
12.8 kDa
Manufacturer - Format
Powder
Description
Human BMP-2 Protein, premium grade (BM2-H4117) is expressed from E. coli cells. It contains AA Ala 284 - Arg 396 (Accession # NP_001191).
Background
Human bone morphogenetic protein 2 (BMP2) is also known as human BMP-2, BMP-2, BMP2, BMP 2, h-BMP-2, rh-BMP-2, recombinant human BMP-2, recombinant BMP-2, BMP, is a member of the BMP subgroup belonging to the TGF-b superfamily of structurally related signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. As implied by its name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP2 has been demonstrated to potently induce osteoblast differentiation in a variety of cell types, and induce apoptosis in human myeloma cell lines as a novel function.
Molecule
BMP-2
Exp Region
Ala 284 - Arg 396
Characteristics
This protein carries no "tag". The protein has a calculated MW of 12.8 kDa. The protein migrates as 14 kDa under reducing (R) condition, and 28 kDa under non-reducing (NR) condition (SDS-PAGE)
Endotoxin
0.2 EU per μg
Buffer
100 mM Acetic Acid, pH2.8
Stability
● -20°C to -70°C for 12 months in lyophilized state;
● -70°C for 3 months under sterile conditions after reconstitution._x000D_For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant
trehalose

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 1 mg
Lieferbar: In stock
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