ArtNr |
BAR-H82E3-200ug |
Hersteller |
ACROBiosystems
|
Menge |
200 ug |
Kategorie |
|
Typ |
Proteins Recombinant |
Format |
Powder |
Specific against |
Human |
Host |
HEK293 |
Konjugat/Tag |
Biotin, HIS, Avi |
Purity |
90% |
Citations |
(1) Thompson JS., et al.,2001, Science, 293 (5537): 2108-2111. (2) Mbrose CM., 2003, Journal of Biological Regulators and Homeostatic Agents, 16 (3): 211-213. (3) Treml LS., et al., 2006, Seminars in Immunology, 18 (5): 297-304. |
ECLASS 5.1 |
34160400 |
ECLASS 6.1 |
34160400 |
ECLASS 8.0 |
42020190 |
ECLASS 9.0 |
42020190 |
ECLASS 10.0.1 |
32160409 |
ECLASS 10.1 |
32160409 |
ECLASS 11.0 |
32160409 |
UNSPSC |
12352202 |
Alias |
BAFFR,TNFRSF13C,BROMIX,CD268,CVID4,prolixin,BAFF-R |
Lieferbar |
|
Manufacturers Category |
Protein / MABSol® Biotin Labeled Proteins |
Description |
Biotinylated Human BAFFR, His, Avitag (BAR-H82E3) is expressed from human 293 cells (HEK293). It contains AA Ser 7 - Ala 71 (Accession # Q96RJ3-1). |
Molecule |
BAFFR |
Exp Region |
Ser 7 - Ala 71 |
Storage |
-20℃ |
Shipping |
RT |
Stability |
-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution.
For long term storage, the product should be stored at lyophilized state at -20°C or lower. |
Molecular Weight |
10.1 kDa |
Characteristics |
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 10.1 kDa. The protein migrates as 15-22 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation. |
Endotoxin |
1.0 EU per μg |
Buffer |
PBS, pH7.4 |
Background |
BAFF receptor (B-cell activating factor receptor, BAFF-R), also known as tumor necrosis factor receptor superfamily member 13C (TNFRSF13C), is a membrane protein of the TNF receptor superfamily which recognizes BAFF. B-cell activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of BAFF in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. |
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