SARS-CoV-2 S1 RBD Protein

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2/COVID-19) Spike S1 Receptor-Binding Domain (RBD) Protein is a recombinant protein expressed in HEK293 cells.

The SARS-CoV-2 Spike Protein (S protein) is a viral protein that allows the entry of SARS-CoV-2 into human cells. The protein forms trimers on the viral capsid and binds to human Angiotensin Converting Enzyme 2 (ACE2) located on the cell surface. The protein has a cleavage site between the S1 and S2 subunits that is targeted by the human enzyme Furin, and it may also cause the development of a syncytium (cell fusion). Antibodies to S protein can prevent viral entry as well as target the virus for further immune action.

1X PBS, pH 7.2. Does not contain preservatives.

~29.5 kDa

Virus

Store unopened at -80 °C. Working aliquots can be prepared and stored at or below -20 °C for up to 3 months. Avoid repeated freeze/thaw cycles.