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Recombinant Human Ubiquitin Conjugating Enzyme E2A

Recombinant Human Ubiquitin Conjugating Enzyme E2A

ArtNr	enz-514-25ug
Hersteller	ProSpec
Menge	25ug
Kategorie	Neuroscience Neural Lineage Markers Peptides & Proteins Enzymes
Typ	Enzymes
Specific against	Human
ECLASS 10.1	32160410
ECLASS 11.0	32160410
UNSPSC	12352204
Similar products	UBE2A
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Synonyms	HHR6A, HR6A, RAD6A, UBC2, UBE2A, EC=6 3 2 19, Ubiquitin-conjugating enzyme E2 A, Ubiquitin-protein ligase A, Ubiquitin carrier protein A, RAD6 homolog A
Introduction	The alteration of proteins with ubiquitin is a vital cellular mechanism for targeting atypical or short-lived proteins for degradation. Ubiquitination involves noT less than three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. UBE2A is part of the E2 ubiquitin-conjugating enzyme family. UBE2A is necessary for post-replicative DNA damage repair. UBE2A catalyzes the covalent attachment of ubiquitin to other proteins. UBE2A is necessary for postreplication repair of UV-damaged DNA.
Description	UBE2A Human Recombinant produced in E.Coli is a single, non-glycosylated, polypeptide chain containing 172 amino acids (1-152 a.a.) and having a molecular mass of 19.4 kDa. UBE2A protein is fused to a 20 amino acid His tag at N-terminus and is purified by standard chromatography.
Source	Escherichia Coli.
Physical Appearance	Sterile filtered colorless solution.
Formulation	UBE2A Human solution containing 20mM Trsi HCL pH-8, 1mM DTT, 1mM EDTA & 10% glycerol.
Purity	Greater than 95% as determined by SDS-PAGE.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Amino acid sequence	MGSSHHHHHH SSGLVPRGSH MSTPARRRLM RDFKRLQEDP PAGVSGAPSE NNIMVWNAVI FGPEGTPFED GTFKLTIEFT EEYPNKPPTV RFVSKMFHPN VYADGSICLD ILQNRWSPTY DVSSILTSIQ SLLDEPNPNS PANSQAAQLY QENKREYEKR VSAIVEQSWR DC.
Storage	UBE2A Human although stable at 4C for 1 week, should be stored desiccated below -18C. Please prevent freeze thaw cycles.

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enz-514-25ug-safety-datasheet.pdf