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Mouse Anti Human Thiopurine S-methyltransferase

Mouse Anti Human Thiopurine S-methyltransferase

ArtNr	ant-055-100ug
Hersteller	ProSpec
Menge	100ug
Kategorie	Antibodies Primary Antibodies
Typ	Antibody Monoclonal
Clon	PAT2E7AT
Specific against	Human
Host	Mouse
ECLASS 10.1	42030590
ECLASS 11.0	42030590
UNSPSC	12352203
Lieferbar
Synonyms	TPMT, Thiopurine S-methyltransferase, EC 2 1 1 67, Thiopurine methyltransferase
Introduction	TPMT, thiopurine S-methyltransferase, is a cytosolic enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. TPMT activity exhibits autosomal codominant genetic polymorphism, and patients inheriting TPMT-deficiency are at high risk of potentially fatal hematopoietic toxicity.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Immunogen	Anti-human TPMT mAb, is derived from hybridization of mouse FO myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TPMT amino acids 1-245 purified from E. coli.
Purification Method	TPMT antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Storage	For periods up to 1 month store at 4C, for longer periods of time, store at -20C. Prevent freeze thaw cycles.

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ant-055-100ug-safety-datasheet.pdf