2,3-dinor-11β-Prostaglandin F2α

2, 3-dinor-11β-Prostaglandin F2α (2, 3-dinor-11β-PGF2α) was recovered from the urine of both normal monkeys and humans when infused with radiolabeled PGD2, where it represented approximately 1% and 4% of the infused radiolabeled dose, respectively. 2, 3-dinor-11β-PGF2α has also been recovered from the urine of mastocytosis patients, where it is excreted in large amounts. In human asthmatic patients, 2, 3-dinor-11β-PGF2α represents about 40% (as determined by GC/MS) of the immunoreactive 11β-PGF2α when measured using 's 11β-PGF2α EIA Kit . The excretion rate for 2, 3-dinor-11β-PGF2α is approximately 200-250 ng/24 hours in a normal adult.

-20°