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Biotinylated SARS-CoV-2 Spike RBD Protein, His,Avitag™ (BA.2.86/Denmark/EPI_ISL_18114953) (MALS verified)

Biotinylated SARS-CoV-2 Spike RBD Protein, His,Avitag™ (BA.2.86/Denmark/EPI_ISL_18114953) (MALS verified)

ArtNr	SPD-C82Q6-200ug
Hersteller	ACROBiosystems
Menge	200 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Powder
Specific against	SARS-CoV-2
Host	HEK293
Konjugat/Tag	Biotin, HIS, Avi
Purity	90%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Lieferbar
Manufacturers Category	Protein / MABSol® Biotin Labeled Proteins
Description	Biotinylated SARS-CoV-2 Spike RBD Protein, His, Avitag (BA.2.86/EPI_ISL_18114953) (SPD-C82Q6) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (I332V, G339H, K356T, S371F, S373P, S375F, T376A, R403K, D405N, R408S, K417N, N440K, V445H, G446S, N450D, L452W, N460K, S477N, T478K, N481K, V483del, E484K, F486P, Q498R, N501Y, Y505H)). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.2.86/Denmark/EPI_ISL_18114953).
Molecule	Spike RBD
Exp Region	Arg 319 - Lys 537
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	28.4 kDa
Characteristics	This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 28.4 kDa. The protein migrates as 37-41 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Background	It's been reported that coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 200 ug

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Lieferung vsl. bis 27.09.2024

Express-Lieferung: 3 Tage sparen

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