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SARS-CoV-2 Spike RBD Protein, His Tag (BA.2.12.1/Omicron) (MALS verified)

SARS-CoV-2 Spike RBD Protein, His Tag (BA.2.12.1/Omicron) (MALS verified)

ArtNr	SPD-C522q-1mg
Hersteller	ACROBiosystems
Menge	1 mg
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Powder
Specific against	SARS-CoV-2
Host	HEK293
Konjugat/Tag	Unconjugated, HIS
Purity	95%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Spike,S protein RBD,Spike glycoprotein Receptor-binding domain,S glycoprotein RBD,Spike protein RBD
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Manufacturers Category	Protein / Viral Proteins
Description	SARS-CoV-2 Spike RBD, His Tag (BA.2.12.1/Omicron) (SPD-C522q) is expressed from human 293 cells (HEK293). It contains AA Arg 319 - Lys 537 (Accession # QHD43416.1 (G339D, S371F, S373P, S375F, T376A, D405N, R408S, K417N, N440K, L452Q, S477N, T478K, E484A, Q493R, Q498R, N501Y, Y505H)). The spike mutations are identified on the SARS-CoV-2 Omicron variant (Pango lineage: BA.2.12.1; GISAID clade: GRA).
Molecule	Spike RBD
Exp Region	Arg 319 - Lys 537
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	26.7 kDa
Characteristics	This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.7 kDa. The protein migrates as 34-37 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Background	It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

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Menge: 1 mg

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Lieferung vsl. bis 06.09.2024

Express-Lieferung: 3 Tage sparen

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