ArtNr |
RD219816A-120uL |
Hersteller |
Reddot Biotech
|
Menge |
120 uL |
Applikationen |
IHC, ELISA |
Specific against |
Human |
Host |
Rabbit |
Isotype |
IgG |
Konjugat/Tag |
Unconjugated |
Alias |
CLMF,CLMF p40,CLMF2,Cytotoxic lymphocyte maturation factor 40 kDa subunit,IL 12B,IL-12 subunit p40,IL-12B,IL12 p40,IL12B,IMD28,IMD29,Interleukin 12 beta chain,Interleukin 12 p40,Interleukin-12 subunit beta,NK cell stimulatory factor chain 2,NKSF,NKSF2 |
Lieferbar |
|
Storage |
Store at -20℃. Avoid freeze / thaw cycles. |
Format (Type) |
Polyclonal Antibody |
Manufactures Category |
Antibodies |
Background |
Interleukin-12 (IL-12), is a cytokine that is secreted by activated phagocytes and dendritic cells and that induces interferon-γproduction by natural-killer and T lymphocytes. IL-12 is a 75 kDa heterodimer composed of a 35 kDa subunit (IL-12A p35) and a 40 kDa subunit (IL-12B p40) that is secreted by a wide variety of antigen presenting cells (APCs), including phagocytes, B cells and Langerhans cells. IL-12B has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of IL-12B was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of IL-12B has been reported to be associated with the severity of atopic and non-atopic asthma in children. |
Concentration |
1.32 mg/mL |
Immunogen |
Synthetic peptide of human IL12B |
Buffer |
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4 |
Purification Method |
Antigen affinity purification |
Dilution |
IHC 1:40-1:200, ELISA 1:5000-1:10000 |
Clonality |
Polyclonal |
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