ArtNr |
NKM-ATGP4102-500ug |
Hersteller |
NKMAX
|
Menge |
500ug |
Applikationen |
SDS-PAGE |
Specific against |
Human |
Konjugat/Tag |
His-Tag |
Purity |
> 95% by SDS-PAGE |
Citations |
Ravetch JV., et al. (1989) J Exp Med. 170:481-497.<br> Ferrara C., et al. (2011) Proc Natl Acad Sci U S A. 108:12669-12674. |
NCBI |
NP_001121065.1 |
Alias |
Low affinity immunoglobulin gamma Fc region receptor III-A,low affinity immunoglobulin gamma Fc region receptor III-A isoform c, IgG Fc receptor III-A, CD16-II, CD16a antigen, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcgammaRIIIA, FcR-10, IgG Fc receptor III-2, CD16a, FCGR3A, CD16A, FCG3, FCGR3, FCGRIII, IGFR3, IMD20, CD16 |
Similar products |
ATGP4102-10ug, ATGP4102-20ug, ATGP4102-50ug, ATGP4102-100ug, ATGP4102-250ug, ATGP4102-500ug, ATGP4102-1mg, ATGP4102-10, ATGP4102-20, ATGP4102-50, ATGP4102-100, ATGP4102-250, ATGP4102-500, ATGP4102-1, ATGP3449-10ug, ATGP3449-20ug, ATGP3449-50ug, ATGP3449-100ug, ATGP3449-250ug, ATGP3449-500ug, ATGP3449-1mg, ATGP3449-10, ATGP3449-20, ATGP3449-50, ATGP3449-100, ATGP3449-250, ATGP3449-500, ATGP3449-1 |
Lieferbar |
|
Domain |
18-208aa |
Description |
FCGR3A, also known as low affinity immunoglobulin gamma Fc region receptor III-A, is a multifunctional, low or intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is expressed on human NK cells as an integral membrane glycoprotein anchored through a transmembrane peptide. It mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. Recombinant human FCGR3A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques. |
Concentration |
0.25mg/ml (determined by absorbance at 280nm) |
Formulation |
Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol |
Storage |
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
Bioactivity Comment Only |
Measured by its binding ability in a functional ELISA with Human IgG1 Fc (CAT# ATGP4094). |
Manufacturers Gene Category |
Immunology |
Molecular Weight |
22.8 kDa (200aa) |
Endotoxin |
< 1 EU per 1ug of protein (determined by LAL method) |
Bioactivity Comment and Pics |
Human Fc gamma RIIIA/CD16a is coated at 10 ug/ml (100 ul/well) can bind Human IgG1 Fc (CAT# ATGP4094) in a functional ELISA assay. |
Bioassay Procedure |
MRTEDLP KAVVFLEPQW YRVLEKDSVT LKCQGAYSPE DNSTQWFHNE SLISSQASSY FIDAATVDDS GEYRCQTNLS TLSDPVQLEV HIGWLLLQAP RWVFKEEDPI HLRCHSWKNT ALHKVTYLQN GKGRKYFHHN SDFYIPKATL KDSGSYFCRG LFGSKNVSSE TVNITITQGL AVSTISSFFP PGYQ |
Expression System |
Baculovirus |
Predicted nterm |
Ala |
Manufacturers Product Type |
Recombinant Protein |
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