« Zurück
Home /
Recombinant human CD16a/FCGR3A protein

Recombinant human CD16a/FCGR3A protein

ArtNr	NKM-ATGP4102-500ug
Hersteller	NKMAX
Menge	500ug
Applikationen	SDS-PAGE
Specific against	Human
Konjugat/Tag	His-Tag
Purity	> 95% by SDS-PAGE
Citations	Ravetch JV., et al. (1989) J Exp Med. 170:481-497.<br> Ferrara C., et al. (2011) Proc Natl Acad Sci U S A. 108:12669-12674.
NCBI	NP_001121065.1
Alias	Low affinity immunoglobulin gamma Fc region receptor III-A,low affinity immunoglobulin gamma Fc region receptor III-A isoform c, IgG Fc receptor III-A, CD16-II, CD16a antigen, Fc-gamma RIII-alpha, Fc-gamma RIII, Fc-gamma RIIIa, FcRIII, FcRIIIa, FcgammaRIIIA, FcR-10, IgG Fc receptor III-2, CD16a, FCGR3A, CD16A, FCG3, FCGR3, FCGRIII, IGFR3, IMD20, CD16
Similar products	ATGP4102-10ug, ATGP4102-20ug, ATGP4102-50ug, ATGP4102-100ug, ATGP4102-250ug, ATGP4102-500ug, ATGP4102-1mg, ATGP4102-10, ATGP4102-20, ATGP4102-50, ATGP4102-100, ATGP4102-250, ATGP4102-500, ATGP4102-1, ATGP3449-10ug, ATGP3449-20ug, ATGP3449-50ug, ATGP3449-100ug, ATGP3449-250ug, ATGP3449-500ug, ATGP3449-1mg, ATGP3449-10, ATGP3449-20, ATGP3449-50, ATGP3449-100, ATGP3449-250, ATGP3449-500, ATGP3449-1
Lieferbar
Domain	18-208aa
Description	FCGR3A, also known as low affinity immunoglobulin gamma Fc region receptor III-A, is a multifunctional, low or intermediate affinity receptor, which belongs to the immunoglobulin superfamily. It is expressed on human NK cells as an integral membrane glycoprotein anchored through a transmembrane peptide. It mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. Recombinant human FCGR3A, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Concentration	0.25mg/ml (determined by absorbance at 280nm)
Formulation	Liquid in. Phosphate-Buffered Saline (pH 7.4) containing 10% glycerol
Storage	Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles.
Bioactivity Comment Only	Measured by its binding ability in a functional ELISA with Human IgG1 Fc (CAT# ATGP4094).
Manufacturers Gene Category	Immunology
Molecular Weight	22.8 kDa (200aa)
Endotoxin	< 1 EU per 1ug of protein (determined by LAL method)
Bioactivity Comment and Pics	Human Fc gamma RIIIA/CD16a is coated at 10 ug/ml (100 ul/well) can bind Human IgG1 Fc (CAT# ATGP4094) in a functional ELISA assay.
Bioassay Procedure	MRTEDLP KAVVFLEPQW YRVLEKDSVT LKCQGAYSPE DNSTQWFHNE SLISSQASSY FIDAATVDDS GEYRCQTNLS TLSDPVQLEV HIGWLLLQAP RWVFKEEDPI HLRCHSWKNT ALHKVTYLQN GKGRKYFHHN SDFYIPKATL KDSGSYFCRG LFGSKNVSSE TVNITITQGL AVSTISSFFP PGYQ
Expression System	Baculovirus
Predicted nterm	Ala
Manufacturers Product Type	Recombinant Protein

Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.

Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

Produkdatenblatt anfordern

Sicherheitsdatenblatt anfordern

Einfache Bestellung Periodische Bestellung

Menge: 500ug

lieferbar

Lieferung vsl. bis 04.10.2024

Express-Lieferung: 16 Tage sparen

Vergleichen

Auf den Wunschzettel

Weiterempfehlen per Mail