ArtNr |
NKM-ATGP0329-250ug |
Hersteller |
NKMAX
|
Menge |
250ug |
Applikationen |
SDS-PAGE |
Specific against |
Human |
Konjugat/Tag |
His-Tag |
Purity |
> 90% by SDS-PAGE |
Citations |
Yu H., et al. (2009), Proteomics. 9(3):504-11.<br> Morita H., et al. (2008). N Engl J Med. 358(18):1899-908.<br> |
NCBI |
NP_001001431.1 |
Alias |
Troponin T type 2 cardiac isoform 3, Troponin T type 2, cardiac isoform 3, CMH2, CMPD2, cTnT, RCM3, TnTC, Troponin T type 2, cardiac isoform 3 Cardiac muscle troponin T, MGC3889, TNNT 2, TNNT2, Cardiomyopathy hypertrophic 2, Cardiomyopathy dilated 1D (autosomal dominant), CMD1D, Troponin T cardiac muscle, Troponin T type 2 (cardiac), Troponin T type 2 cardiac, Troponin T2 cardiac. |
Similar products |
CMPD2, TNNT2, cTnT, CMH2, MGC3889, RCM3, TnTC, Troponin T, CMD1D, Troponin T type 2 (cardiac), Cardiomyopathy dilated 1D (autosomal dominant), Cardiomyopathy hypertrophic 2, TNNT 2, Troponin T cardiac muscle, Troponin T type 2 cardiac, Troponin T2 cardiac, Troponin T type 2 cardiac isoform 3, Troponin T type 2, cardiac isoform 3, Troponin T type 2, cardiac isoform 3 Cardiac muscle troponin T, ATGP0329-100, ATGP0329-10ug, ATGP0329-20ug, ATGP0329-50ug, ATGP0329-100ug, ATGP0329-250ug, ATGP0329-500ug, ATGP0329-1mg, ATGP0329-10, ATGP0329-20, ATGP0329-50, ATGP0329-100, ATGP0329-250, ATGP0329-500, ATGP0329-1 |
Lieferbar |
|
Domain |
1-285aa |
Description |
Troponin T, also known as TNNT2, is the tropomyosin-binding subunit of the troponin complex, which is located on the thin filament of striated muscles and regulates muscle contraction in response to alterations in intracellular calcium ion concentration. Mutations in this gene have been associated with familial hypertrophic cardiomyopathy as well as with restrictive and dilated cardiomyopathy. Recombinant human TNNT2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography. |
Concentration |
0.25mg/ml (determined by Bradford assay) |
Formulation |
Liquid in. 20mM Tris-HCl buffer (pH 8.0) containing 50% glycerol, 0.5M NaCl, 0.1mM PMSF, 1mM DTT, 100mM imidazole |
Storage |
Can be stored at +2C to +8C for 1 week. For long term storage, aliquot and store at -20C to -80C. Avoid repeated freezing and thawing cycles. |
Manufacturers Gene Category |
Cytoskeleton |
Molecular Weight |
36.4 kDa (305aa) confirmed by MALDI-TOF |
Bioassay Procedure |
MSDIEEVVEE YEEEEQEEAA VEEQEEAAEE DAEAEAETEE TRAEEDEEEE EAKEAEDGPM EESKPKPRSF MPNLVPPKIP DGERVDFDDI HRKRMEKDLN ELQALIEAHF ENRKKEEEEL VSLKDRIERR RAERAEQQRI RNEREKERQN RLAEERARRE EEENRRKAED EARKKKALSN MMHFGGYIQK TERKSGKRQT EREKKKKILA ERRKVLAIDH LNEDQLREKA KELWQSIYNL EAEKFDLQEK FKQQKYEINV LRNRINDNQK VSKTRGKAKV TGRWK |
Expression System |
E.coli |
Manufacturers Product Type |
Recombinant Protein |
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