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Human IL-7 R alpha&TSLP R Heterodimer Protein, Fc Tag&Fc Tag

Human IL-7 R alpha&TSLP R Heterodimer Protein, Fc Tag&Fc Tag

ArtNr	ILR-H525x-1mg
Hersteller	ACROBiosystems
Menge	1 mg
Quantity options	100 ug 1 mg
Kategorie	Peptides & Proteins Amino Acids
Typ	Proteins
Format	Powder
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	Fc, Unconjugated
Purity	95%
NCBI	NP_002176.2 , NP_071431.2
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	IL7Ra,CD127,TSLP R,CRLF2,IL-XR,ILXR,p2RY8,CRLF2 fusion,TSLP receptor,TSLPR,CRL2,CRLF2Y,Cytokine receptor-like 2
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Protein / Other Recombinant Proteins
Manufacturer - Conjugate / Tag	C-Fc \| C-Fc, Unconjugated
Shipping Temperature	RT
Storage Conditions	-20°C
Molecular Weight	51.7 kDa (IL-7 RA) & 50.3 kDa (TSLP R)
Description	Human IL-7 RA&TSLP R Heterodimer Protein, Fc Tag&Fc Tag (ILR-H525x) is expressed from human 293 cells (HEK293). It contains AA Glu 21 - Asp 239 (IL-7RA) & Gln 23 - Lys 231 (TSLPR) (Accession # P16871-1 (IL-7RA) & Q9HC73-1 (TSLPR)).
Background	TSLP is a pleiotropic cytokine originally characterized as a lymphocyte growth factor. Thymic stromal lymphopoietin (TSLP) is overexpressed in the airways of severe asthmatics and is an upstream cytokine that orchestrates inflammatory responses in asthma. Human TSLP exerts its biological activities by binding to a high-affinity heteromeric receptor complex composed of TSLPR and IL- 7 receptor and initiates signaling in cells co-expressing TSLPR and IL-7R.
Molecule	IL-7 R alpha & TSLP R
Exp Region	Glu 21 - Asp 239 (IL-7RA) & Gln 23 - Lys 231 (TSLPR)
Characteristics	Human IL-7 RA&TSLP R Heterodimer Protein, Fc Tag&Fc Tag is produced by co-expression of IL-7 RA and TSLP R, has a calculated MW of 51.7 kDa (IL-7 RA) and 50.3 kDa (TSLP R). Subunit IL-7 RA is fused with a human IgG1 Fc fragment at the C-terminus and subunit TSLP R is fused with a human IgG1 Fc fragment at the C-terminus. The reducing (R) protein migrates as 60-70 kDa due to glycosylation.
Endotoxin	1.0 EU per μg
Buffer	PBS, pH7.4
Stability	● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Protectant	trehalose

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ILR-H525x-1mg-datasheet.pdf

ILR-H525x-1mg-safety-datasheet.pdf