Product Description |
The REG4 protein is a calcium-dependent lectin that functions as a pattern recognition receptor (PRR) in the innate immune system. REG4 has specific affinity for α-mannan on Candida albicans hyphae and triggers phosphorylation of the FCER1G immunoreceptor tyrosine activation motif (ITAM), thereby activating SYK, CARD9 and NF-kappa-B. REG4 Protein, Rat (HEK293, Fc) is the recombinant rat-derived REG4 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of REG4 Protein, Rat (HEK293, Fc) is 157 a.a., with molecular weight of ~49 kDa. |