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Human FGF-10 / KGF 2 Protein, His Tag, premium grade

Human FGF-10 / KGF 2 Protein, His Tag, premium grade

ArtNr	FG0-H5145-100ug
Hersteller	ACROBiosystems
Menge	100 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Powder
Specific against	Human
Host	E.coli
Konjugat/Tag	Unconjugated, HIS
Purity	95%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	FGF-10,Fibroblast growth factor 10,Keratinocyte growth factor 2
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Manufacturers Category	Protein / Cytokines&Growth Factors
Description	Human FGF-10 Protein, His Tag, premium grade (FG0-H5145) is expressed from E. coli cells. It contains AA Gln 38 - Ser 208 (Accession # O15520-1).
Molecule	FGF-10
Exp Region	Gln 38 - Ser 208
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	21.2 kDa
Characteristics	This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 21.2 kDa. The protein migrates as 27 kDa under reducing (R) condition (SDS-PAGE).
Endotoxin	0.1 EU per μg
Buffer	20 mM MOPS, 200 mM NaCl, 100 mM Na2SO4, 1mM EDTA, 1mM DTT, pH7.0
Background	Fibroblast Growth Factor 10 (FGF 10) is an evolutionary conserved secreted growth factor mediating mostly mesenchymal to epithelial signaling. FGF 10 belongs to the FGF 7 subfamily and shares similar biochemical and amino acid sequences with its constituent members (FGF3, FGF 7 and FGF 22). As a paracrine FGF, FGF 10 elicits its biological responses by activating the fibroblast growth factor receptor 2b (FGF R 2b), is crucial for governing proximal distal outgrowth as well as patterning and acts upstream of the known apical ectodermal ridge (AER) marker FGF 8. FGF10 is also implicated in pancreatic cancer, and that overexpression of FGFR2b is associated with metastatic invasion.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 ug

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Lieferung vsl. bis 30.08.2024

Express-Lieferung: 2 Tage sparen

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