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Human CXCL4 / PF4 Protein, His Tag Europäischer Partner

ArtNr CX4-H52H9-100ug
Hersteller ACROBiosystems
Menge 100 ug
Kategorie
Typ Proteins Recombinant
Format Powder
Specific against Human
Host HEK293
Konjugat/Tag Unconjugated, HIS
Purity 95%
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias PF4,CXCL4,MGC138298,SCYB4, C-X-C motif chemokine 4, Iroplact, Oncostatin-A
Lieferbar
Manufacturers Category
Protein / Other Recombinant Proteins
Description
Human CXCL4, His Tag (CX4-H52H9) is expressed from human 293 cells (HEK293). It contains AA Glu 32 - Ser 101 (Accession # P02776-1).
Molecule
CXCL4
Exp Region
Glu 32 - Ser 101
Storage
-20℃
Shipping
RT
Stability
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight
9.7 kDa
Characteristics
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 9.7 kDa. The protein migrates as 13 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
10 mM Sodium Citrate, 150 mM NaCl, pH5.0
Background
CXCL4, or Platelet factor 4 (PF4), is a small cytokine belonging to the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. CXCL4 is chemotactic for neutrophils and monocytes and also functions as an inhibitor of hematopoiesis, angiogenesis and T-cell function. CXCL4/PF4 is up-regulated in human liver fibrosis and that it plays a nonredundant, functional role in experimental liver fibrosis by mediating stellate cell proliferation, migration, and intrahepatic immune cell recruitment.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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