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Human CD45RA / PTPRC protein, His Tag Europäischer Partner

ArtNr CD5-H52H9-100ug
Hersteller ACROBiosystems
Menge 100 ug
Kategorie
Typ Proteins
Format Powder
Specific against Human
Host HEK293
Konjugat/Tag Unconjugated, HIS
Purity 95%
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CD45,PTPRC,L-CA,T200
Lieferbar
Manufacturers Category
Protein / Bio-Markers & CD Antigens
Description
Human CD45RA / PTPRC protein, His Tag (CD5-H52H9) is expressed from human 293 cells (HEK293). It contains AA Gln 26 - Lys 482 (Accession # P08575-8).
Molecule
CD45RA
Exp Region
Gln 26 - Lys 482
Storage
-20℃
Shipping
RT
Stability
-20°C to -70°C for 12 months in lyophilized state;
-70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight
53.2 kDa
Characteristics
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 53.2 kDa. The protein migrates as 110-120 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin
1.0 EU per μg
Buffer
PBS, pH7.4
Background
CD45 is a receptor protein tyrosine phosphatase, also known as Ly-5 or leukocyte common antigen. CD45 mainly involves in the initiation of T cell receptor signaling by controlling the activation of the Src family protein-tyrosine kinases Lck and Fyn. CD45 deficiency causes in T- and B-lymphocyte dysfunction in the form of severe combined immune deficiency. It also takes a significant role in autoimmune diseases and cancer as well as in infectious diseases including fungal infections.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100 ug
Lieferbar: In stock
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