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Biotinylated Human CD30 / TNFRSF8 Protein, Fc,Avitag™ (MALS verified)

Biotinylated Human CD30 / TNFRSF8 Protein, Fc,Avitag™ (MALS verified)

ArtNr	CD0-H82F4-200ug
Hersteller	ACROBiosystems
Menge	200 ug
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Powder
Specific against	Human
Host	HEK293
Konjugat/Tag	Biotin, Avi, Fc
Purity	90%
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	TNFRSF8,CD30,D1S166E,Ki-1
Lieferbar
Manufacturers Category	Protein / MABSol® Biotin Labeled Proteins
Description	Biotinylated Human CD30, Fc, Avitag (CD0-H82F4) is expressed from human 293 cells (HEK293). It contains AA Phe 19 - Lys 379 (Accession # NP_001234.2).
Molecule	CD30
Exp Region	Phe 19 - Lys 379
Storage	-20℃
Shipping	RT
Stability	-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Molecular Weight	66.6 kDa
Characteristics	This protein carries a human IgG1 Fc tag at the C-terminus, followed by an Avi tag (Avitag™). The protein has a calculated MW of 66.6 kDa. The protein migrates as 80-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Endotoxin	0.1 EU per μg
Buffer	50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Background	Human CD30 is also known as TNFRSF8, is a cell membrane protein of the tumor necrosis factor receptor family and tumor marker. TNFRSF-8 is expressed by activated, but not by resting, T and B cells. Also, CD30 is expressed on classical Hodgkin Lymphoma cells together with CD15. CD30 is the receptor for TNFSF8/CD30L. CD30 can interact with TRAF2 and TRAF5, and mediate the signal transduction that leads to the activation of NF-kappa-B. TNFRSF8 may play a role in the regulation of cellular growth and transformation of activated lymphoblasts. TNFRSF8 is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 200 ug

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Lieferung vsl. bis 23.08.2024

Express-Lieferung: 2 Tage sparen

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