ArtNr |
BOS-PROTP21246-5ug |
Hersteller |
Boster
|
Menge |
5ug |
Format |
Lyophilized Powder |
Specific against |
Human |
Konjugat/Tag |
HIS |
Dry ice |
Yes
|
Sequence |
<MKHHHHHHHM LVPRGS> GKKE KPEKKVKKSD CGEWQWSVCV PTSGDCGLGT REGTRTGAEC KQTMKTQRCK IPCNWKKQFG AECKYQFQAW GECDLNTALK TRTGSLKRAL HNAECQKTVT ISKPCGKLTK PKPQAESKKK KKEGKKQEKM LD |
Alias |
PTN; Heparin Affin Regulatory Protein; HARP; Heparin-binding growth factor-8; HBGF-8; Osteoblast-Specific Factor-1; OSF-1; Heparin-binding growth-associated molecule; HB-GAM; HBNF-1 Heparin-binding brain mitogen; Heparin-binding neurite outgrowth-promoting factor 1; HBBM; NEGF1 |
Lieferbar |
|
Manufacturers Product Category |
Recombinant Proteins |
Short Description |
Pleiotrophin Human Recombinant contains His-Tagged Fusion Protein, produced in E. coli, its molecular weight is 17.3 kDa protein containing 136 amino acid residues of the OSF-1 human and 16 additional amino acid residues - HisTag, thrombin cleavage site (underlined). |
Description |
Pleiotrophin Human Recombinant contains His-Tagged Fusion Protein, produced in E. coli, its molecular weight is 17.3 kDa protein containing 136 amino acid residues of the OSF-1 human and 16 additional amino acid residues - HisTag, thrombin cleavage site (underlined). |
Gene Name |
PTN |
Contents |
Filtered and lyophilized from 0.5 mg/ml in 0.1M phosphate buffer and 0.1M NaCl, pH 7.2. |
Purification |
Greater than 95% as determined by SDS-PAGE. |
Storage |
Store lyophilized protein at -20°C. Aliquot the product after reconstitution to avoid repeated freezing/thawing cycles. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after two weeks at 4°C. |
Reconstitution |
Add PBS pH 7.2 and let the lyophilized pellet dissolve completely. |
Gene Full Name |
Pleiotrophin |
Protein Function |
Secreted growth factor that induces neurite outgrowth and which is mitogenic for fibroblasts, epithelial, and endothelial cells. Binds anaplastic lymphoma kinase (ALK) which induces MAPK pathway activation, an important step in the anti- apoptotic signaling of PTN and regulation of cell proliferation. |
Subcellular Localization |
Secreted. |
Tissue Specificity |
Osteoblast and brain. |
Format Information |
Filtered White lyophilized (freeze-dried) powder. |
Hinweis: Die dargestellten Informationen und Dokumente (Bedienungsanleitung, Produktdatenblatt, Sicherheitsdatenblatt und Analysezertifikat) entsprechen unserem letzten Update und sollten lediglich der Orientierung dienen. Wir übernehmen keine Garantie für die Aktualität. Für spezifische Anforderungen bitten wir Sie, uns eine Anfrage zu stellen.
Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.