ArtNr |
BOS-PROTP07339-10ug |
Hersteller |
Boster
|
Menge |
10ug |
Format |
Solution |
Specific against |
other |
Dry ice |
Yes
|
Sequence |
LVRIPLHKFT SIRRTMSEVG GSVEDLIAKG PVSKYSQAVP AVTEGPIPEV LKNYMDAQYY GEIGIGTPPQ CFTVVFDTGS SNLWVPSIHC KLLDIACWIH HKYNSDKSST YVKNGTSFDI HYGSGSLSGY LSQDTVSVPC QSASSASALG GVKVERQVFG EATKQPGITF IAAKFDGILG MAYPRISVNN VLPVFDNLMQ QKLVDQNIFS FYLSRDPDAQ PGGELMLGGT DS |
Alias |
Cathepsin D; EC 3.4.23.5; CTSD; CPSD; CLN10; MGC2311 |
Lieferbar |
|
Manufacturers Product Category |
Recombinant Proteins |
Short Description |
CTSD produced in HEK293 cells is a single, glycosylated polypeptide chain containing 398 amino acids (21-412 a.a.) and having a molecular mass of 43.4kDa. CTSD is expressed with an 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques. |
Description |
CTSD produced in HEK293 cells is a single, glycosylated polypeptide chain containing 398 amino acids (21-412 a.a.) and having a molecular mass of 43.4kDa. CTSD is expressed with an 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques. |
Gene Name |
CTSD |
Contents |
CTSD at 1mg/ml in 50mM MES, pH5.5, 100mM NaCl and 20% Glycerol. |
Purification |
Greater than 95% as determined by SDS-PAGE |
Storage |
Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.Please prevent freeze-thaw cycles. |
Gene Full Name |
Cathepsin D |
Protein Function |
Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease. |
Subcellular Localization |
Lysosome. Melanosome. Secreted, extracellular space. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In aortic samples, detected as an extracellular protein loosely bound to the matrix (PubMed:20551380). |
Tissue Specificity |
Expressed in the aorta extrcellular space (at protein level). |
Format Information |
Sterile Filtered clear solution. |
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