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CTSD Cathepsin-D Human Recombinant Protein Europäischer Partner

ArtNr BOS-PROTP07339-10ug
Hersteller Boster
Menge 10ug
Format Solution
Specific against other
Dry ice Yes
Sequence LVRIPLHKFT SIRRTMSEVG GSVEDLIAKG PVSKYSQAVP AVTEGPIPEV LKNYMDAQYY GEIGIGTPPQ CFTVVFDTGS SNLWVPSIHC KLLDIACWIH HKYNSDKSST YVKNGTSFDI HYGSGSLSGY LSQDTVSVPC QSASSASALG GVKVERQVFG EATKQPGITF IAAKFDGILG MAYPRISVNN VLPVFDNLMQ QKLVDQNIFS FYLSRDPDAQ PGGELMLGGT DS
Alias Cathepsin D; EC 3.4.23.5; CTSD; CPSD; CLN10; MGC2311
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Manufacturers Product Category
Recombinant Proteins
Short Description
CTSD produced in HEK293 cells is a single, glycosylated polypeptide chain containing 398 amino acids (21-412 a.a.) and having a molecular mass of 43.4kDa. CTSD is expressed with an 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Description
CTSD produced in HEK293 cells is a single, glycosylated polypeptide chain containing 398 amino acids (21-412 a.a.) and having a molecular mass of 43.4kDa. CTSD is expressed with an 6 amino acid His tag at C-Terminus and purified by proprietary chromatographic techniques.
Gene Name
CTSD
Contents
CTSD at 1mg/ml in 50mM MES, pH5.5, 100mM NaCl and 20% Glycerol.
Purification
Greater than 95% as determined by SDS-PAGE
Storage
Store vial at -20°C to -80°C. When stored at the recommended temperature, this protein is stable for 12 months.Please prevent freeze-thaw cycles.
Gene Full Name
Cathepsin D
Protein Function
Acid protease active in intracellular protein breakdown. Involved in the pathogenesis of several diseases such as breast cancer and possibly Alzheimer disease.
Subcellular Localization
Lysosome. Melanosome. Secreted, extracellular space. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In aortic samples, detected as an extracellular protein loosely bound to the matrix (PubMed:20551380).
Tissue Specificity
Expressed in the aorta extrcellular space (at protein level).
Format Information
Sterile Filtered clear solution.

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Menge: 10ug
Lieferbar: In stock
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