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Anti-ITLN1 Antibody Picoband™

Anti-ITLN1 Antibody Picoband™

ArtNr	BOS-PB10004-10ug
Hersteller	Boster
Menge	10ug
Format	Lyophilized
Applikationen	WB, FC, IF, IHC, ICC
Specific against	Human
Host	Rabbit
Isotype	IgG
Alias	Intelectin-1;ITLN-1;Endothelial lectin HL-1;Galactofuranose-binding lectin;Intestinal lactoferrin receptor;Omentin;ITLN1;INTL, ITLN, LFR;UNQ640/PRO1270;
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Manufacturers Product Category	Primary Antibodies, Rabbit Polyclonal Antibodies
Manufacturers Research Category	Cancer, Cardiovascular, Lipid Metabolism, Lipids/Lipoproteins, Metabolism, Signal Transduction
Short Description	Boster Bio Anti-ITLN1 Antibody Picoband™ catalog # PB10004. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human.
Description	Boster Bio Anti-ITLN1 Antibody Picoband™ catalog # PB10004. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human.
Background	Intelectin-1, also known as omentin, is an intelectin encoded in humans by the ITLN1 gene. This gene is mapped to chromosome 1q21.3-q22 by genomic sequence analysis. It is expressed on multiple cell types and appears to participate in insulin signaling and microbe recognition. Intelectin-1 functions both as a receptor for bacterial arabinogalactans and for lactoferrin. Having conserved ligand binding site residues, both human and mouse intelectin-1 bind the exocyclic vicinal diol of carbohydrate ligands such as galactofuranose.
Gene Name	ITLN1
Application Details	Western blot, 0.1-0.5μg/ml, Human Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, By Heat Immunocytochemistry/Immunofluorescence, 2μg/ml, Human Flow Cytometry, 1-3μg/1x10⁶ cells, Human
Application Notes	Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.
Clonality	Polyclonal
Concentration	Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Contents	Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunogen	A synthetic peptide corresponding to a sequence at the N-terminus of human ITLN1.
Purification	Immunogen affinity purified.
Cross-reactivity	No cross-reactivity with other proteins
Storage	Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Reconstitution	Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Gene Full Name	Intelectin-1
Molecular Weight	34962 MW
Protein Function	Has no effect on basal glucose uptake but enhances insulin-stimulated glucose uptake in adipocytes. Increases AKT phosphorylation in the absence and presence of insulin. May play a role in the defense system against microorganisms. May specifically recognize carbohydrate chains of pathogens and bacterial components containing galactofuranosyl residues, in a calcium-dependent manner. May be involved in iron metabolism..
Subcellular Localization	Cell membrane ; Lipid-anchor, GPI-anchor. Secreted. Enriched in lipid rafts..
Tissue Specificity	Highly expressed in omental adipose tissue where it is found in stromal vascular cells but not in fat cells but is barely detectable in subcutaneous adipose tissue (at protein level). Highly expressed in the small intestine. Also found in the heart, testis, colon, salivary gland, skeletal muscle, pancreas and thyroid and, to a lesser degree, in the uterus, spleen, prostate, lymph node and thymus..
Protein Name	Intelectin-1

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Menge: 10ug

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Lieferung vsl. bis 04.10.2024

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