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Anti-IL2 Receptor beta/IL2RB Antibody Europäischer Partner

ArtNr BOS-PA1615-10ug
Hersteller Boster
Menge 10ug
Format Lyophilized
Applikationen WB
Specific against Human
Host Rabbit
Isotype IgG
Alias Interleukin-2 receptor subunit beta;IL-2 receptor subunit beta;IL-2R subunit beta;IL-2RB;High affinity IL-2 receptor subunit beta;p70-75;p75;CD122;IL2RB;
Lieferbar
Manufacturers Product Category
Primary Antibodies, Rabbit Polyclonal Antibodies
Manufacturers Research Category
Adaptive Immunity, Cytokines, Hematopoietic Progenitors, Immunology, Innate Immunity, Interleukins, Lymphoid, Myeloid, Protein Phosphorylation, Receptor Tyrosine Kinases, Signal Transduction, Stem Cells, Tyrosine Kinases
Short Description
Boster Bio Anti-IL2 Receptor beta/IL2RB Antibody catalog # PA1615. Tested in WB applications. This antibody reacts with Human.
Description
Boster Bio Anti-IL2 Receptor beta/IL2RB Antibody catalog # PA1615. Tested in WB applications. This antibody reacts with Human.
Background
IL2RB (INTERLEUKIN 2 RECEPTOR, BETA), also called CD122, is a protein that in humans is encoded by the IL2RB gene. The gene represents the beta subunit and is a type I membrane protein. IL2RB is mapped to 22q12.3. The IL2RB gene contains 10 exons spanning about 24.3 kb and that the gene product is encoded by exons 2-10. The IL2 receptor is present in 3 forms with respect to binding ability to IL2: high, intermediate, and low affinity forms. Analysis of mutants of the beta chain of the IL2 receptor reveals that the granulocyte and monocyte differentiation signals are triggered by different cytoplasmic domains, showing that the signaling pathways responsible for these unique developmental outcomes are separable.
Gene Name
IL2RB
Application Details
Western blot, 0.1-0.5μg/ml, Human
Application Notes
Tested Species: In-house tested species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
Clonality
Polyclonal
Concentration
Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.
Contents
Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Immunogen
A synthetic peptide corresponding to a sequence in the middle region of human IL2RB.
Purification
Immunogen affinity purified.
Cross-reactivity
No cross-reactivity with other proteins
Storage
Store at -20˚C for one year from date of receipt. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for six months. Avoid repeated freeze-thaw cycles.
Reconstitution
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Gene Full Name
Interleukin-2 receptor subunit beta
Molecular Weight
61117 MW
Protein Function
Receptor for interleukin-2. This beta subunit is involved in receptor mediated endocytosis and transduces the mitogenic signals of IL2.
Subcellular Localization
Membrane; Single-pass type I membrane protein.
Protein Name
Interleukin-2 receptor subunit beta(IL-2 receptor subunit beta/IL-2R subunit beta/IL-2RB)
Sequence Similarities
Belongs to the type I cytokine receptor family. Type 4 subfamily.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10ug
Lieferbar: In stock
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