Anti-Dopamine Receptor D1/DRD1 Antibody

Primary Antibodies, Rabbit Polyclonal Antibodies

Boster Bio Anti-Dopamine Receptor D1/DRD1 Antibody catalog # PA1571. Tested in IHC, WB applications. This antibody reacts with Human, Mouse, Rat.

Dopamine receptor D1, also known as DRD1, is a human gene. It is the most highly expressed DA receptor subtype among the DA receptor family. Receptors for dopamine have been classified into two functional types, D1 and D2. They belong to the family of receptors acting through G (or guanine nucleotide-binding) proteins. D2 receptors inhibit adenylyl cyclase, but D1 receptors stimulate adenylyl cyclase and activate cyclic AMP-dependent protein kinases. Dopamine D1 and D2 receptors are targets of drug therapy in many psychomotor disorders, including Parkinson's disease and schizophrenia, and may also have a role in drug addiction and alcoholism. D1 receptors regulate neuron growth and differentiation, influence behaviour and modify dopamine D2 receptor-mediated events. And the presence of a D1 receptor gene restriction fragment length polymorphism will be helpful for future disease linkage studies. DRD1 also regulates the neurochemical architecture of the striatum and is critical for the normal expression of motor activity.

Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Rat, Mouse, By Heat
Western blot, 0.1-0.5μg/ml, Human, Rat, Mouse

Hamster

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

A synthetic peptide corresponding to a sequence in the middle region of human DRD1, different from the related rat and mouse sequences by one amino acid.

No cross-reactivity with other proteins

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

49293 MW

Cell membrane ; Multi-pass membrane protein. Endoplasmic reticulum membrane ; Multi-pass membrane protein. Transport from the endoplasmic reticulum to the cell surface is regulated by interaction with DNAJC14..

D(1A) dopamine receptor