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Anti-VE-Cadherin Cdh5-Rabbit Monoclonal Antibody

Anti-VE-Cadherin Cdh5-Rabbit Monoclonal Antibody

ArtNr	BOS-M02632-30ul
Hersteller	Boster
Menge	30ul
Format	Liquid
Applikationen	WB, IF, IP, ICC
Clon	IIC-3
Specific against	Mouse
Host	Rabbit
Isotype	IgG
Sensitivity	<10pg/ml
Alias	Cadherin-5;Vascular endothelial cadherin;VE-cadherin;CD144;Cdh5;
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Manufacturers Product Category	Primary Antibodies, Rabbit Monoclonal Antibodies
Manufacturers Research Category	Atherosclerosis, Cadherins, Cancer, Cardiovascular, Cell Adhesion, Cell Adhesion Molecules, Cytoskeleton/ECM, Invasion/Microenvironment, Signal Transduction, Vascular Inflammation, Vasculature
Short Description	Boster Bio Anti-VE-Cadherin Cdh5-Rabbit Monoclonal Antibody catalog # M02632. Tested in WB, ICC/IF, IP applications. This antibody reacts with Mouse.
Description	Boster Bio Anti-VE-Cadherin Cdh5-Rabbit Monoclonal Antibody catalog # M02632. Tested in WB, ICC/IF, IP applications. This antibody reacts with Mouse.
Gene Name	CDH5
Application Details	WB 1:500-1:1000 ICC/IF 1:500-1:1000 IP 1:50
Clonality	Monoclonal
Concentration	Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Contents	Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Immunogen	A synthesized peptide derived from mouse VE Cadherin
Purification	Affinity-chromatography
Storage	Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Gene Full Name	Cadherin-5
Molecular Weight	87903 MW
Protein Function	Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. This cadherin may play an important role in endothelial cell biology through control of the cohesion and organization of the intercellular junctions. Acts in concert with KRIT1 to establish and maintain correct endothelial cell polarity and vascular lumen. These effects are mediated by recruitment and activation of the Par polarity complex and RAP1B. Required for activation of PRKCZ and for localization of phosphorylated PRKCZ, PARD3, TIAM1 and RAP1B to the cell junction..
Subcellular Localization	Cell junction. Cell membrane ; Single-pass type I membrane protein. Found at cell-cell boundaries and probably at cell-matrix boundaries. KRIT1 and CDH5 reciprocally regulate their localization to endothelial cell-cell junctions (By similarity)..

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 30ul

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Lieferung vsl. bis 30.08.2024

Express-Lieferung: 3 Tage sparen

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